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Research ArticleResearch Article: New Research, Disorders of the Nervous System

Enhanced Synaptic Inhibition in the Dorsolateral Geniculate Nucleus in a Mouse Model of Glaucoma

Matthew J. Van Hook and Shaylah McCool
eNeuro 27 June 2024, 11 (7) ENEURO.0263-24.2024; https://doi.org/10.1523/ENEURO.0263-24.2024
Matthew J. Van Hook
1Department of Ophthalmology and Visual Sciences, Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, Nebraska 68198
2Departments of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, Nebraska 68198
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Shaylah McCool
1Department of Ophthalmology and Visual Sciences, Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, Nebraska 68198
3Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska 68198
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0263-24.2024
PubMed 
38937109
Published By 
Society for Neuroscience
History 
  • Received June 13, 2024
  • Accepted June 20, 2024
  • Published online June 27, 2024.
Copyright & Usage 
Copyright © 2024 Van Hook and McCool This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Matthew J. Van Hook1,2 and
  2. Shaylah McCool1,3
  1. 1Department of Ophthalmology and Visual Sciences, Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, Nebraska 68198
  2. 2Departments of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, Nebraska 68198
  3. 3Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska 68198
  1. Correspondence should be addressed to Matthew J. Van Hook at matt.vanhook{at}unmc.edu.
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Author contributions

  1. Author contributions: M.J.V.H. designed research; M.J.V.H. and S.M. performed research; M.J.H. and S.M. analyzed data; M.J.H. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by National Institutes of Health–National Eye Institute Grant R01EY030507 and a Career Advancement Award from Research to Prevent Blindness (RPB) and The Glaucoma Foundation to M.J.H. The funders had no role in study design, data collection, analysis, decision to publish, or manuscript preparation. We are grateful to Jennie Smith for performing intraocular pressure measurements.

Funding

  • HHS | NIH | National Eye Institute (NEI)

    EY030507
  • Research to Prevent Blindness (RPB)

  • The Glaucoma Foundation

Other Version

  • You are viewing the most recent version of this article.
  • previous version (June 27, 2024).

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Article usage: June 2024 to January 2026

AbstractFullPdf
Jun 202499035
Jul 2024261297193
Aug 20244017147
Sep 20241810723
Oct 20241310126
Nov 20241410325
Dec 20241011837
Total 2024455897386
Jan 20251111740
Feb 20251011320
Mar 20251113630
Apr 2025511437
May 20251010931
Jun 20251211331
Jul 20251010132
Aug 202549530
Sep 20251918426
Oct 20251010631
Nov 2025612118
Dec 20251010940
Total 20251181418366
Jan 202654720
Total 202654720
Total5782362772
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eneuro: 11 (7)
eNeuro
Vol. 11, Issue 7
July 2024
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Enhanced Synaptic Inhibition in the Dorsolateral Geniculate Nucleus in a Mouse Model of Glaucoma
Matthew J. Van Hook, Shaylah McCool
eNeuro 27 June 2024, 11 (7) ENEURO.0263-24.2024; DOI: 10.1523/ENEURO.0263-24.2024

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Enhanced Synaptic Inhibition in the Dorsolateral Geniculate Nucleus in a Mouse Model of Glaucoma
Matthew J. Van Hook, Shaylah McCool
eNeuro 27 June 2024, 11 (7) ENEURO.0263-24.2024; DOI: 10.1523/ENEURO.0263-24.2024
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Keywords

  • GABA
  • glaucoma
  • homeostatic plasticity
  • inhibition
  • synaptic scaling
  • thalamus

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