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Research ArticleResearch Article: New Research, Disorders of the Nervous System

Aberrant Functional Connectivity of the Salience Network in Adult Patients with Tic Disorders: A Resting-State fMRI Study

Linda Orth, Johanna Meeh, Delia Leiding, Ute Habel, Irene Neuner and Pegah Sarkheil
eNeuro 14 May 2024, 11 (6) ENEURO.0223-23.2024; https://doi.org/10.1523/ENEURO.0223-23.2024
Linda Orth
1Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, 52074 Aachen, Germany
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Johanna Meeh
2Department of Psychiatry and Psychotherapy, University of Münster, 48149 Münster, Germany
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Delia Leiding
1Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, 52074 Aachen, Germany
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Ute Habel
1Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, 52074 Aachen, Germany
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Irene Neuner
1Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, 52074 Aachen, Germany
3Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Jülich, 52428 Jülich, Germany
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Pegah Sarkheil
1Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, 52074 Aachen, Germany
2Department of Psychiatry and Psychotherapy, University of Münster, 48149 Münster, Germany
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0223-23.2024
PubMed 
38744491
Published By 
Society for Neuroscience
History 
  • Received June 21, 2023
  • Revision received December 27, 2023
  • Accepted February 26, 2024
  • Published online May 14, 2024.
Copyright & Usage 
Copyright © 2024 Orth et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Linda Orth1,
  2. Johanna Meeh2,
  3. Delia Leiding1,
  4. Ute Habel1,
  5. Irene Neuner1,3 and
  6. Pegah Sarkheil1,2
  1. 1Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, 52074 Aachen, Germany
  2. 2Department of Psychiatry and Psychotherapy, University of Münster, 48149 Münster, Germany
  3. 3Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Jülich, 52428 Jülich, Germany
  1. Correspondence should be addressed to Pegah Sarkheil at pegah.sarkheil{at}ukmuenster.de.
View Full Text

Author contributions

  1. Author contributions: L.O., D.L., U.H., I.N., and P.S. designed research; L.O. and D.L. performed research; L.O., J.M., U.H., I.N., and P.S. analyzed data; L.O. wrote the paper.

View Abstract

Disclosures

  • The authors declare no competing financial interests.

  • This research was funded by the Deutsche Forschungsgemeinschaft (German Research Foundation) No. 269953372, No. 448334688, and No. NE1585/7-1) and the START program of the Rheinisch-Westfalische Technische Hochschule (RWTH) Aachen University. This work was supported by the Brain Imaging Facility of the Interdisciplinary Center for Clinical Research Aachen within the Faculty of Medicine at RWTH Aachen University.

Funding

  • Deutsche Forschungsgemeinschaft (DFG)

    269953372; NE1585/7-1; 448334688

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  • You are viewing the most recent version of this article.
  • previous version (May 14, 2024).

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May 20242190116
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eneuro: 11 (6)
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June 2024
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Aberrant Functional Connectivity of the Salience Network in Adult Patients with Tic Disorders: A Resting-State fMRI Study
Linda Orth, Johanna Meeh, Delia Leiding, Ute Habel, Irene Neuner, Pegah Sarkheil
eNeuro 14 May 2024, 11 (6) ENEURO.0223-23.2024; DOI: 10.1523/ENEURO.0223-23.2024

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Aberrant Functional Connectivity of the Salience Network in Adult Patients with Tic Disorders: A Resting-State fMRI Study
Linda Orth, Johanna Meeh, Delia Leiding, Ute Habel, Irene Neuner, Pegah Sarkheil
eNeuro 14 May 2024, 11 (6) ENEURO.0223-23.2024; DOI: 10.1523/ENEURO.0223-23.2024
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Keywords

  • functional connectivity
  • insula
  • non-tic symptoms
  • resting-state fMRI
  • salience network
  • tic disorder

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