Article Information
- Received January 24, 2024
- Revision received March 22, 2024
- Accepted April 16, 2024
- Published online May 24, 2024.
Author Information
- Maryam Rahmati1,
- Jasmine Chebli1,
- Rakesh Kumar Banote1,
- Sandra Roselli1,
- Lotta Agholme1,
- Henrik Zetterberg1,2,3,4,5,6 and
- Alexandra Abramsson1
- 1Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden
- 2Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N #BG, United Kingdom
- 3Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal 431 41, Sweden
- 4United Kingdom Dementia Research Institute, London W1T 7NF, United Kingdom
- 5Hong Kong Center for Neurodegenerative Diseases, 17 Science Park W Ave, Hong Kong, China
- 6Wisconsin Alzheimer’s Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin 53792
- Correspondence should be addressed to Alexandra Abramsson at alexandra.abramsson{at}gu.se.
Author contributions
Author contributions: R.K.B., H.Z., and A.A. designed research; M.R., J.C., R.K.B., S.R., L.A., and A.A. performed research; M.R., J.C., R.K.B., S.R., L.A., and A.A. analyzed data; M.R., J.C., H.Z., and A.A. wrote the paper.
Disclosures
The authors declare no competing financial interests.
We thank Elisa Alexandersson and Katarina Türner Stenström for fish maintenance, Olav Andersen (Aarhus, Denmark) for kindly sharing the human APP:GFP plasmid, Erna Pervan for RNA preparation and sequencing, Emma Västerviga and Katarina Truvé for statistical/bioinformatics analyses from Genomics and Bioinformatics Core Facility platforms at the Sahlgrenska Academy, University of Gothenburg. The study was supported by grants from the Swedish Research Council (#2022-01018 and #2019-02397), the European Union’s Horizon Europe Research and Innovation Programme under grant agreement (#101053962), and Swedish State Support for Clinical Research (#ALFGBG-71320). H.Z. is a Wallenberg Scholar.
Funding
Vetenskapsrådet (VR)
2019-02397; 2022-01018Swedish State Support for Clinical Research
ALFGBG-71320European Union's Horizon Europe research and innovation programme
101053962
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