Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT

User menu

Search

  • Advanced search
eNeuro
eNeuro

Advanced Search

 

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT
PreviousNext
Research ArticleResearch Article: New Research, Cognition and Behavior

Structural Neuroplasticity Effects of Singing in Chronic Aphasia

Aleksi J. Sihvonen, Anni Pitkäniemi, Sini-Tuuli Siponkoski, Linda Kuusela, Noelia Martínez-Molina, Sari Laitinen, Essi-Reetta Särkämö, Johanna Pekkola, Susanna Melkas, Gottfried Schlaug, Viljami Sairanen and Teppo Särkämö
eNeuro 30 April 2024, 11 (5) ENEURO.0408-23.2024; https://doi.org/10.1523/ENEURO.0408-23.2024
Aleksi J. Sihvonen
1Cognitive Brain Research Unit and Centre of Excellence in Music, Mind, Body and Brain, Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland
2School of Health and Rehabilitation Sciences, Queensland Aphasia Research Centre and UQ Centre for Clinical Research, The University of Queensland, Brisbane QLD 4072, Australia
3Department of Neurology, University of Helsinki and Helsinki University Hospital, Helsinki 00029, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Aleksi J. Sihvonen
Anni Pitkäniemi
1Cognitive Brain Research Unit and Centre of Excellence in Music, Mind, Body and Brain, Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sini-Tuuli Siponkoski
1Cognitive Brain Research Unit and Centre of Excellence in Music, Mind, Body and Brain, Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Linda Kuusela
4HUS Helsinki Medical Imaging Center, Helsinki University Hospital, Helsinki 00029, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Noelia Martínez-Molina
1Cognitive Brain Research Unit and Centre of Excellence in Music, Mind, Body and Brain, Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sari Laitinen
5Espoo Hospital, Espoo 00029, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Essi-Reetta Särkämö
6Private Choir Conductor, Vantaa 01520, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Johanna Pekkola
4HUS Helsinki Medical Imaging Center, Helsinki University Hospital, Helsinki 00029, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Susanna Melkas
3Department of Neurology, University of Helsinki and Helsinki University Hospital, Helsinki 00029, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Gottfried Schlaug
7Department of Neurology, UMass Medical School, Springfield, Massachusetts 01655
8Department of Biomedical Engineering and Institute of Applied Life Sciences, UMass Amherst, Amherst, Massachusetts 01655
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Viljami Sairanen
4HUS Helsinki Medical Imaging Center, Helsinki University Hospital, Helsinki 00029, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Teppo Särkämö
1Cognitive Brain Research Unit and Centre of Excellence in Music, Mind, Body and Brain, Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Teppo Särkämö
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/ENEURO.0408-23.2024
PubMed 
38688718
Published By 
Society for Neuroscience
History 
  • Received October 13, 2023
  • Revision received February 28, 2024
  • Accepted April 18, 2024
  • Published online April 30, 2024.
Copyright & Usage 
Copyright © 2024 Sihvonen et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Aleksi J. Sihvonen1,2,3,*,
  2. Anni Pitkäniemi1,*,
  3. Sini-Tuuli Siponkoski1,
  4. Linda Kuusela4,
  5. Noelia Martínez-Molina1,
  6. Sari Laitinen5,
  7. Essi-Reetta Särkämö6,
  8. Johanna Pekkola4,
  9. Susanna Melkas3,
  10. Gottfried Schlaug7,8,
  11. Viljami Sairanen4 and
  12. Teppo Särkämö1
  1. 1Cognitive Brain Research Unit and Centre of Excellence in Music, Mind, Body and Brain, Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland
  2. 2School of Health and Rehabilitation Sciences, Queensland Aphasia Research Centre and UQ Centre for Clinical Research, The University of Queensland, Brisbane QLD 4072, Australia
  3. 3Department of Neurology, University of Helsinki and Helsinki University Hospital, Helsinki 00029, Finland
  4. 4HUS Helsinki Medical Imaging Center, Helsinki University Hospital, Helsinki 00029, Finland
  5. 5Espoo Hospital, Espoo 00029, Finland
  6. 6Private Choir Conductor, Vantaa 01520, Finland
  7. 7Department of Neurology, UMass Medical School, Springfield, Massachusetts 01655
  8. 8Department of Biomedical Engineering and Institute of Applied Life Sciences, UMass Amherst, Amherst, Massachusetts 01655
  1. Correspondence should be addressed to Aleksi J. Sihvonen at aleksi.sihvonen{at}helsinki.fi.
View Full Text

Author contributions

  1. Author contributions: A.J.S., A.P., S.-T.S., L.K., S.L., E.-R.S., S.M., G.S., V.S., and T.S. designed research; A.P., S.-T.S., L.K., S.L., and E.-R.S. performed research; A.J.S., A.P., S.-T.S., N.M.-M., J.P., and T.S. analyzed data; A.J.S., S.-T.S., L.K., N.M.-M., S.L., E.-R.S., J.P., S.M., G.S., V.S., and T.S. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • We thank Andrea Norton and Jeanette Tamplin as well as all the PSA participants and their family members for their invaluable input in this project. This study was supported by the Academy of Finland (Grants 299044, 306625, 327996, and 346211), Fundació La Marató de TV3 (Grant 201729.32), and European Research Council (Grant 803466). A.J.S received funding from the Finnish Cultural Foundation (Grant 191230), the Orion Research Foundation, and the Signe and Ane Gyllenberg Foundation, and V.S. was supported by Instrumentarium Science Foundation sr and Orion Research Foundation sr.

  • ↵*A.J.S. and A.P. contributed equally to this work.

Funding

  • Research Council of Finland (AKA)

    299044
  • Fundacio La Marato

    201729.32
  • EC | ERC | HORIZON EUROPE European Research Council (ERC)

    803466
  • Suomen Kulttuurirahasto (SKR)

    191230
  • Orion | Orionin Tutkimussäätiö (Orion Research Foundation)

  • Signe ja Ane Gyllenbergin Säätiö (Signe and Ane Gyllenberg Foundation)

  • Instrumentariumin Tiedesäätiö (Instrumentarium Science Foundation)

Other Version

  • You are viewing the most recent version of this article.
  • previous version (April 30, 2024).

Online Impact

 

Article usage

Select a custom date range for the past year
E.g., 2025-11-12
to
E.g., 2025-11-12

Article usage: April 2024 to November 2025

AbstractFullPdf
Apr 20241903
May 20243981754492
Jun 202472477163
Jul 20242831983
Aug 20243125570
Sep 202446315122
Oct 202427317116
Nov 202479339118
Dec 202431449163
Total 202473142251330
Jan 202536275108
Feb 202550417142
Mar 202550413179
Apr 202536450173
May 202525428165
Jun 202534337149
Jul 20252429981
Aug 20252329886
Sep 20252247497
Oct 202524548192
Nov 20251621846
Total 202534041571418
Total107183822748
Back to top

In this issue

eneuro: 11 (5)
eNeuro
Vol. 11, Issue 5
May 2024
  • Table of Contents
  • Index by author
  • Masthead (PDF)
Email

Thank you for sharing this eNeuro article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Structural Neuroplasticity Effects of Singing in Chronic Aphasia
(Your Name) has forwarded a page to you from eNeuro
(Your Name) thought you would be interested in this article in eNeuro.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
Structural Neuroplasticity Effects of Singing in Chronic Aphasia
Aleksi J. Sihvonen, Anni Pitkäniemi, Sini-Tuuli Siponkoski, Linda Kuusela, Noelia Martínez-Molina, Sari Laitinen, Essi-Reetta Särkämö, Johanna Pekkola, Susanna Melkas, Gottfried Schlaug, Viljami Sairanen, Teppo Särkämö
eNeuro 30 April 2024, 11 (5) ENEURO.0408-23.2024; DOI: 10.1523/ENEURO.0408-23.2024

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Share
Structural Neuroplasticity Effects of Singing in Chronic Aphasia
Aleksi J. Sihvonen, Anni Pitkäniemi, Sini-Tuuli Siponkoski, Linda Kuusela, Noelia Martínez-Molina, Sari Laitinen, Essi-Reetta Särkämö, Johanna Pekkola, Susanna Melkas, Gottfried Schlaug, Viljami Sairanen, Teppo Särkämö
eNeuro 30 April 2024, 11 (5) ENEURO.0408-23.2024; DOI: 10.1523/ENEURO.0408-23.2024
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Significance Statement
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Footnotes
    • References
    • Synthesis
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • aphasia
  • music
  • rehabilitation
  • singing
  • stroke
  • structural connectivity

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

Research Article: New Research

  • A progressive ratio task with costly resets reveals adaptive effort-delay tradeoffs
  • What is the difference between an impulsive and a timed anticipatory movement ?
  • Psychedelics Reverse the Polarity of Long-Term Synaptic Plasticity in Cortical-Projecting Claustrum Neurons
Show more Research Article: New Research

Cognition and Behavior

  • Visual Speech Reduces Cognitive Effort as Measured by EEG Theta Power and Pupil Dilation
  • A progressive ratio task with costly resets reveals adaptive effort-delay tradeoffs
  • Luminance Matching in Cognitive Pupillometry Is Not Enough: The Curious Case of Orientation
Show more Cognition and Behavior

Subjects

  • Cognition and Behavior
  • Home
  • Alerts
  • Follow SFN on BlueSky
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Latest Articles
  • Issue Archive
  • Blog
  • Browse by Topic

Information

  • For Authors
  • For the Media

About

  • About the Journal
  • Editorial Board
  • Privacy Notice
  • Contact
  • Feedback
(eNeuro logo)
(SfN logo)

Copyright © 2025 by the Society for Neuroscience.
eNeuro eISSN: 2373-2822

The ideas and opinions expressed in eNeuro do not necessarily reflect those of SfN or the eNeuro Editorial Board. Publication of an advertisement or other product mention in eNeuro should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in eNeuro.