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Research ArticleResearch Article: New Research, Cognition and Behavior

Pharmacological Inhibition of the Nucleus Accumbens Increases Dyadic Social Interaction in Macaques

Hannah F. Waguespack, Jessica T. Jacobs, Janis Park, Carolina Campos-Rodriguez, Rafael S. Maior, Patrick A. Forcelli and Ludise Malkova
eNeuro 4 April 2024, 11 (4) ENEURO.0085-24.2024; https://doi.org/10.1523/ENEURO.0085-24.2024
Hannah F. Waguespack
1Interdisciplinary Program in Neuroscience, Georgetown University, Washington, DC 20007
2Department of Pharmacology & Physiology, Georgetown University, Washington, DC 20007
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Jessica T. Jacobs
1Interdisciplinary Program in Neuroscience, Georgetown University, Washington, DC 20007
2Department of Pharmacology & Physiology, Georgetown University, Washington, DC 20007
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Janis Park
2Department of Pharmacology & Physiology, Georgetown University, Washington, DC 20007
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Carolina Campos-Rodriguez
2Department of Pharmacology & Physiology, Georgetown University, Washington, DC 20007
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Rafael S. Maior
2Department of Pharmacology & Physiology, Georgetown University, Washington, DC 20007
3Laboratory of Neurosciences and Behavior, Department of Physiological Sciences, Institute of Biology, University of Brasilia, Brasilia 70.910-900, Brazil
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  • ORCID record for Rafael S. Maior
Patrick A. Forcelli
1Interdisciplinary Program in Neuroscience, Georgetown University, Washington, DC 20007
2Department of Pharmacology & Physiology, Georgetown University, Washington, DC 20007
4Department of Neuroscience, Georgetown University, Washington, DC 20007
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Ludise Malkova
1Interdisciplinary Program in Neuroscience, Georgetown University, Washington, DC 20007
2Department of Pharmacology & Physiology, Georgetown University, Washington, DC 20007
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0085-24.2024
PubMed 
38575350
Published By 
Society for Neuroscience
History 
  • Received February 29, 2024
  • Accepted March 18, 2024
  • Published online April 4, 2024.
Copyright & Usage 
Copyright © 2024 Waguespack et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Hannah F. Waguespack1,2,
  2. Jessica T. Jacobs1,2,
  3. Janis Park2,
  4. Carolina Campos-Rodriguez2,
  5. Rafael S. Maior2,3,
  6. Patrick A. Forcelli1,2,4 and
  7. Ludise Malkova1,2
  1. 1Interdisciplinary Program in Neuroscience, Georgetown University, Washington, DC 20007
  2. 2Department of Pharmacology & Physiology, Georgetown University, Washington, DC 20007
  3. 3Laboratory of Neurosciences and Behavior, Department of Physiological Sciences, Institute of Biology, University of Brasilia, Brasilia 70.910-900, Brazil
  4. 4Department of Neuroscience, Georgetown University, Washington, DC 20007
  1. Correspondence should be addressed to Ludise Malkova at malkoval{at}georgetown.edu or Patrick Forcelli at Paf22{at}georgetown.edu.
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Author contributions

  1. Author contributions: H.F.W., P.A.F., and L.M. designed research; H.F.W., J.T.J., J.P., C.C.-R., R.S.M., and P.A.F. performed research; H.F.W., J.T.J., J.P., C.C-R., P.A.F., and L.M. analyzed data; H.F.W., J.T.J., J.P., C.C.-R., R.S.M., P.A.F., and L.M. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • The study was supported by the National Institutes Health grant R01MH120638.

Funding

  • HHS | NIH | National Institute of Mental Health (NIMH)

    R01MH120638
  • HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)

    T32NS041218

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  • You are viewing the most recent version of this article.
  • previous version (April 04, 2024).

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Pharmacological Inhibition of the Nucleus Accumbens Increases Dyadic Social Interaction in Macaques
Hannah F. Waguespack, Jessica T. Jacobs, Janis Park, Carolina Campos-Rodriguez, Rafael S. Maior, Patrick A. Forcelli, Ludise Malkova
eNeuro 4 April 2024, 11 (4) ENEURO.0085-24.2024; DOI: 10.1523/ENEURO.0085-24.2024

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Pharmacological Inhibition of the Nucleus Accumbens Increases Dyadic Social Interaction in Macaques
Hannah F. Waguespack, Jessica T. Jacobs, Janis Park, Carolina Campos-Rodriguez, Rafael S. Maior, Patrick A. Forcelli, Ludise Malkova
eNeuro 4 April 2024, 11 (4) ENEURO.0085-24.2024; DOI: 10.1523/ENEURO.0085-24.2024
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Keywords

  • dominance
  • dopamine
  • GABA
  • muscimol
  • quinpirole

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