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Research ArticleResearch Article: New Research, Sensory and Motor Systems

Dopamine Receptor-Expressing Neurons Are Differently Distributed throughout Layers of the Motor Cortex to Control Dexterity

Przemyslaw E. Cieslak, Sylwia Drabik, Anna Gugula, Aleksandra Trenk, Martyna Gorkowska, Kinga Przybylska, Lukasz Szumiec, Grzegorz Kreiner, Jan Rodriguez Parkitna and Anna Blasiak
eNeuro 29 February 2024, 11 (3) ENEURO.0490-23.2023; https://doi.org/10.1523/ENEURO.0490-23.2023
Przemyslaw E. Cieslak
1Department of Neurophysiology and Chronobiology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Krakow 30-387, Poland
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Sylwia Drabik
1Department of Neurophysiology and Chronobiology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Krakow 30-387, Poland
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Anna Gugula
1Department of Neurophysiology and Chronobiology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Krakow 30-387, Poland
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  • ORCID record for Anna Gugula
Aleksandra Trenk
1Department of Neurophysiology and Chronobiology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Krakow 30-387, Poland
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Martyna Gorkowska
1Department of Neurophysiology and Chronobiology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Krakow 30-387, Poland
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Kinga Przybylska
1Department of Neurophysiology and Chronobiology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Krakow 30-387, Poland
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Lukasz Szumiec
2Department of Molecular Neuropharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow 31-343, Poland
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Grzegorz Kreiner
3Department of Brain Biochemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow 31-343, Poland
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Jan Rodriguez Parkitna
2Department of Molecular Neuropharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow 31-343, Poland
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Anna Blasiak
1Department of Neurophysiology and Chronobiology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Krakow 30-387, Poland
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0490-23.2023
PubMed 
38423792
Published By 
Society for Neuroscience
History 
  • Received November 22, 2023
  • Revision received December 20, 2023
  • Accepted December 29, 2023
  • Published online February 29, 2024.
Copyright & Usage 
Copyright © 2024 Cieslak et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Przemyslaw E. Cieslak1,
  2. Sylwia Drabik1,
  3. Anna Gugula1,
  4. Aleksandra Trenk1,
  5. Martyna Gorkowska1,
  6. Kinga Przybylska1,
  7. Lukasz Szumiec2,
  8. Grzegorz Kreiner3,
  9. Jan Rodriguez Parkitna2 and
  10. Anna Blasiak1
  1. 1Department of Neurophysiology and Chronobiology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Krakow 30-387, Poland
  2. 2Department of Molecular Neuropharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow 31-343, Poland
  3. 3Department of Brain Biochemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow 31-343, Poland
  1. Correspondence should be addressed to Przemyslaw E. Cieslak at pe.cieslak{at}uj.edu.pl or Anna Blasiak at anna.blasiak{at}uj.edu.pl.
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Author contributions

  1. Author contributions: P.E.C. and A.B. designed research; P.E.C., S.D., A.G., A.T., and K.P. performed research; L.S., G.K., and J.R.P. contributed unpublished reagents/analytic tools; P.E.C., S.D., A.G., A.T., M.G., K.P., and A.B. analyzed data; P.E.C. and A.B. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • We thank Monika Baginska for excellent technical assistance in genotyping and maintaining the colony of transgenic animals.

  • This study was supported by The National Science Centre (Poland) grant SONATINA 2018/28/C/NZ4/00102 (to P.E.C.).

Funding

  • The National Science Centre (Poland)

    2018/28/C/NZ4/00102

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Dopamine Receptor-Expressing Neurons Are Differently Distributed throughout Layers of the Motor Cortex to Control Dexterity
Przemyslaw E. Cieslak, Sylwia Drabik, Anna Gugula, Aleksandra Trenk, Martyna Gorkowska, Kinga Przybylska, Lukasz Szumiec, Grzegorz Kreiner, Jan Rodriguez Parkitna, Anna Blasiak
eNeuro 29 February 2024, 11 (3) ENEURO.0490-23.2023; DOI: 10.1523/ENEURO.0490-23.2023

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Dopamine Receptor-Expressing Neurons Are Differently Distributed throughout Layers of the Motor Cortex to Control Dexterity
Przemyslaw E. Cieslak, Sylwia Drabik, Anna Gugula, Aleksandra Trenk, Martyna Gorkowska, Kinga Przybylska, Lukasz Szumiec, Grzegorz Kreiner, Jan Rodriguez Parkitna, Anna Blasiak
eNeuro 29 February 2024, 11 (3) ENEURO.0490-23.2023; DOI: 10.1523/ENEURO.0490-23.2023
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Keywords

  • dopamine
  • motor cortex
  • skill learning

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