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Research ArticleResearch Article: New Research, Neuronal Excitability

Divergent Changes in PBN Excitability in a Mouse Model of Neuropathic Pain

María L. Torruella-Suárez, Benjamin Neugebauer, Krystal Flores-Felix, Asaf Keller, Yarimar Carrasquillo and Nathan Cramer
eNeuro 8 February 2024, 11 (3) ENEURO.0416-23.2024; https://doi.org/10.1523/ENEURO.0416-23.2024
María L. Torruella-Suárez
1National Center for Complementary and Integrative Health, National Institutes of Health, Bethesda, Maryland 20892
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Benjamin Neugebauer
1National Center for Complementary and Integrative Health, National Institutes of Health, Bethesda, Maryland 20892
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Krystal Flores-Felix
2Department of Neurobiology and UM-MIND, University of Maryland School of Medicine, Baltimore, Maryland 21201
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Asaf Keller
2Department of Neurobiology and UM-MIND, University of Maryland School of Medicine, Baltimore, Maryland 21201
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Yarimar Carrasquillo
1National Center for Complementary and Integrative Health, National Institutes of Health, Bethesda, Maryland 20892
3National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland 20892
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Nathan Cramer
2Department of Neurobiology and UM-MIND, University of Maryland School of Medicine, Baltimore, Maryland 21201
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0416-23.2024
PubMed 
38331576
Published By 
Society for Neuroscience
History 
  • Received October 16, 2023
  • Revision received December 19, 2023
  • Accepted January 17, 2024
  • Published online February 8, 2024.
Copyright & Usage 
Copyright © 2024 Torruella-Suárez et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. María L. Torruella-Suárez1,
  2. Benjamin Neugebauer1,
  3. Krystal Flores-Felix2,
  4. Asaf Keller2,
  5. Yarimar Carrasquillo1,3 and
  6. Nathan Cramer2
  1. 1National Center for Complementary and Integrative Health, National Institutes of Health, Bethesda, Maryland 20892
  2. 2Department of Neurobiology and UM-MIND, University of Maryland School of Medicine, Baltimore, Maryland 21201
  3. 3National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland 20892
  1. Correspondence should be addressed to Nathan Cramer at ncramer{at}som.umaryland.edu.
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Author contributions

  1. Author contributions: M.L.T-S., B.N., K.F-F., A.K., Y.C., and N.C. designed research; M.L.T-S., B.N., K.F-F., and N.C. performed research; A.K. and Y.C. contributed unpublished reagents/analytic tools; M.L.T-S., B.N., K.F-F., and N.C. analyzed data; M.L.T-S., A.K., Y.C., and N.C. wrote the paper.

Disclosures

  • The authors declare no conflict financial interests.

  • This work was supported by the National Institutes of Health National Institute (NIH) of Neurological Disorders and Stroke Grants R01NS099245 (to A.K.), R01NS069568 (to A.K.), and R01NS127827 (to N.C.) and the Intramural Research Program at the NIH National Center for Complementary and Integrative Health (to Y.C.). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The funding sources had no role in study design; the collection, analysis and interpretation of data; the writing of the report; or in the decision to submit the article for publication.

Funding

  • HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)

    R01NS099245; R01NS069568; 1R01NS127827
  • HHS | NIH | National Center for Complementary and Integrative Health (OAM)

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  • You are viewing the most recent version of this article.
  • previous version (February 08, 2024).

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eneuro: 11 (3)
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March 2024
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Divergent Changes in PBN Excitability in a Mouse Model of Neuropathic Pain
María L. Torruella-Suárez, Benjamin Neugebauer, Krystal Flores-Felix, Asaf Keller, Yarimar Carrasquillo, Nathan Cramer
eNeuro 8 February 2024, 11 (3) ENEURO.0416-23.2024; DOI: 10.1523/ENEURO.0416-23.2024

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Divergent Changes in PBN Excitability in a Mouse Model of Neuropathic Pain
María L. Torruella-Suárez, Benjamin Neugebauer, Krystal Flores-Felix, Asaf Keller, Yarimar Carrasquillo, Nathan Cramer
eNeuro 8 February 2024, 11 (3) ENEURO.0416-23.2024; DOI: 10.1523/ENEURO.0416-23.2024
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Keywords

  • afterdischarges
  • GABAB
  • intrinsic properties
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  • trigeminal

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