Article Information
- Received January 20, 2023
- Revision received January 12, 2024
- Accepted January 17, 2024
- Published online February 21, 2024.
Author Information
- Charysse Vandendriessche1,2,*,
- Arnout Bruggeman1,2,3,*,
- Joyce Foroozandeh1,2,4,5,
- Lien Van Hoecke1,2,
- Pieter Dujardin1,2,
- Junhua Xie1,2,
- Griet Van Imschoot1,2,
- Elien Van Wonterghem1,2,
- Jonas Castelein1,2,
- Cristiano Lucci6,
- Lies De Groef6 and
- Roosmarijn E. Vandenbroucke1,2
- 1VIB Center for Inflammation Research, VIB, 9000, Ghent, Belgium
- 2Department of Biomedical Molecular Biology, Ghent University, 9000, Ghent, Belgium
- 3Department of Neurology, Ghent University Hospital, 9000, Ghent, Belgium
- 4VIB Center for Brain & Disease Research, VIB, 3000, Leuven, Belgium
- 5Department of Neurosciences, Brain Institute KU Leuven, 3000, Leuven, Belgium
- 6Cellular Communication and Neurodegeneration Research Group, Department of Biology, Leuven Brain Institute, KU Leuven, 3000, Leuven, Belgium
- Correspondence should be addressed to Roosmarijn E. Vandenbroucke at roosmarijn.vandenbroucke{at}irc.vib-ugent.be.
Author contributions
Author contributions: C.V., A.B., L.D.G., and R.E.V. designed research; C.V., A.B., J.F., L.V.H., P.D., J.X., G.V.I., E.V.W., J.C., and C.L. performed research; C.V., A.B., and R.E.V. analyzed data; C.V., A.B., and R.E.V. wrote the paper.
Disclosures
The authors declare no competing financial interest.
This work was supported by the Research Foundation Flanders (FWO Vlaanderen; 1295223N; 3S001918; 1S54121N; 1268823N; 3F013720), the Special Research Fund (BOF) of Ghent University (01P07621), EU Joint Programme–Neurodegenerative Diseases (S007721N), the Flemish patient association for Parkinson's disease (Vlaamse Parkinson Liga), VIB, and the Fund Baillet Latour. We thank the VIB Bioimaging Core for training, support, and access to the instrument park, the VIB Protein Core for the expression and purification of the α-syn protein, and Kelly Lemeire for performing several of the immunofluorescence stainings. Laura Volpicelli-Daley is acknowledged for providing the plasmid to express human recombinant full-length monomeric α-syn protein (NM_000345).
↵*C.V. and A.B. contributed equally to this work.
Funding
Research Foundation Flanders
1295223N; 3S001918; 1S54121N; 1268823N; 3F013720Special Research Fund Ghent University
01P07621Flemish patient association for Parkinson's research
VIB
Fund Baillet Latour
EU Joint Programme - Neurodegenerative Diseases
S007721N
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