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Research ArticleResearch Article: New Research, Disorders of the Nervous System

Astrocyte-Derived Exosomal miR-148a-3p Suppresses Neuroinflammation and Restores Neurological Function in Traumatic Brain Injury by Regulating the Microglial Phenotype

Yan Qian, Xin Li, Guiliang Li, Huali Liu, Qiaofen Li, Xia Liu, Yang Zhang, Zongying He, Ying Zhao and Hong Fan
eNeuro 25 January 2024, 11 (2) ENEURO.0336-23.2024; https://doi.org/10.1523/ENEURO.0336-23.2024
Yan Qian
1Rehabilitation Medicine, Qujing No.1 Hospital, Qujing, Yunnan 655000, China
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Xin Li
1Rehabilitation Medicine, Qujing No.1 Hospital, Qujing, Yunnan 655000, China
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Guiliang Li
1Rehabilitation Medicine, Qujing No.1 Hospital, Qujing, Yunnan 655000, China
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Huali Liu
1Rehabilitation Medicine, Qujing No.1 Hospital, Qujing, Yunnan 655000, China
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Qiaofen Li
1Rehabilitation Medicine, Qujing No.1 Hospital, Qujing, Yunnan 655000, China
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Xia Liu
1Rehabilitation Medicine, Qujing No.1 Hospital, Qujing, Yunnan 655000, China
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Yang Zhang
1Rehabilitation Medicine, Qujing No.1 Hospital, Qujing, Yunnan 655000, China
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Zongying He
1Rehabilitation Medicine, Qujing No.1 Hospital, Qujing, Yunnan 655000, China
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Ying Zhao
2Rehabilitation Medicine, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650000, China
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Hong Fan
2Rehabilitation Medicine, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650000, China
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eneuro: 11 (2)
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February 2024
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Astrocyte-Derived Exosomal miR-148a-3p Suppresses Neuroinflammation and Restores Neurological Function in Traumatic Brain Injury by Regulating the Microglial Phenotype
Yan Qian, Xin Li, Guiliang Li, Huali Liu, Qiaofen Li, Xia Liu, Yang Zhang, Zongying He, Ying Zhao, Hong Fan
eNeuro 25 January 2024, 11 (2) ENEURO.0336-23.2024; DOI: 10.1523/ENEURO.0336-23.2024

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Astrocyte-Derived Exosomal miR-148a-3p Suppresses Neuroinflammation and Restores Neurological Function in Traumatic Brain Injury by Regulating the Microglial Phenotype
Yan Qian, Xin Li, Guiliang Li, Huali Liu, Qiaofen Li, Xia Liu, Yang Zhang, Zongying He, Ying Zhao, Hong Fan
eNeuro 25 January 2024, 11 (2) ENEURO.0336-23.2024; DOI: 10.1523/ENEURO.0336-23.2024
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Keywords

  • exosomes
  • inflammatory response
  • microglial phenotype
  • neurological function
  • traumatic brain injury

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