Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT

User menu

Search

  • Advanced search
eNeuro
eNeuro

Advanced Search

 

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT
PreviousNext
Research ArticleResearch Article: New Research, Cognition and Behavior

AD-Like Neuropsychiatric Dysfunction in a Mice Model Induced by a Combination of High-Fat Diet and Intraperitoneal Injection of Streptozotocin

Huaizhi Sun, Xinran Gao, Jiachun Niu, Pengquan Chen, Shuai He, Songlin Xu and Jinfang Ge
eNeuro 3 December 2024, 11 (12) ENEURO.0310-24.2024; https://doi.org/10.1523/ENEURO.0310-24.2024
Huaizhi Sun
1School of Pharmacy, Anhui Medical University, Hefei 230032, PR China
2The Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Medical University, Hefei 230032, PR China
3Anhui Provincial Laboratory of Inflammatory and Immune Disease, Anhui Institute of Innovative Drugs, Hefei 230032, PR China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Xinran Gao
1School of Pharmacy, Anhui Medical University, Hefei 230032, PR China
2The Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Medical University, Hefei 230032, PR China
3Anhui Provincial Laboratory of Inflammatory and Immune Disease, Anhui Institute of Innovative Drugs, Hefei 230032, PR China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jiachun Niu
1School of Pharmacy, Anhui Medical University, Hefei 230032, PR China
2The Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Medical University, Hefei 230032, PR China
3Anhui Provincial Laboratory of Inflammatory and Immune Disease, Anhui Institute of Innovative Drugs, Hefei 230032, PR China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Pengquan Chen
1School of Pharmacy, Anhui Medical University, Hefei 230032, PR China
2The Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Medical University, Hefei 230032, PR China
3Anhui Provincial Laboratory of Inflammatory and Immune Disease, Anhui Institute of Innovative Drugs, Hefei 230032, PR China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Shuai He
1School of Pharmacy, Anhui Medical University, Hefei 230032, PR China
2The Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Medical University, Hefei 230032, PR China
3Anhui Provincial Laboratory of Inflammatory and Immune Disease, Anhui Institute of Innovative Drugs, Hefei 230032, PR China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Songlin Xu
1School of Pharmacy, Anhui Medical University, Hefei 230032, PR China
2The Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Medical University, Hefei 230032, PR China
3Anhui Provincial Laboratory of Inflammatory and Immune Disease, Anhui Institute of Innovative Drugs, Hefei 230032, PR China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jinfang Ge
1School of Pharmacy, Anhui Medical University, Hefei 230032, PR China
2The Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Medical University, Hefei 230032, PR China
3Anhui Provincial Laboratory of Inflammatory and Immune Disease, Anhui Institute of Innovative Drugs, Hefei 230032, PR China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Jinfang Ge
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/ENEURO.0310-24.2024
PubMed 
39626951
Published By 
Society for Neuroscience
History 
  • Received July 14, 2024
  • Revision received November 1, 2024
  • Accepted November 4, 2024
  • Published online December 3, 2024.
Copyright & Usage 
Copyright © 2024 Sun et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Huaizhi Sun1,2,3,*,
  2. Xinran Gao1,2,3,*,
  3. Jiachun Niu1,2,3,
  4. Pengquan Chen1,2,3,
  5. Shuai He1,2,3,
  6. Songlin Xu1,2,3 and
  7. Jinfang Ge1,2,3
  1. 1School of Pharmacy, Anhui Medical University, Hefei 230032, PR China
  2. 2The Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Medical University, Hefei 230032, PR China
  3. 3Anhui Provincial Laboratory of Inflammatory and Immune Disease, Anhui Institute of Innovative Drugs, Hefei 230032, PR China
  1. Correspondence should be addressed to Jinfang Ge at gejinfang{at}ahmu.edu.cn.
View Full Text

Author contributions

  1. Author contributions: J.G. designed research; H.S. and X.G. performed research; H.S., X.G., P.C., and S.H. contributed unpublished reagents/analytic tools; J.N., S.H., and S.X. analyzed data; H.S. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • We thank the Center for Scientific Research of Anhui Medical University for their valuable help in our immunofluorescence experiment. This work was supported by the National Natural Science Foundation of China (81870403), Anhui Province Postgraduate Education Quality Project (2023xscx050), and Scientific Research Promotion Plan of Anhui Medical University (2022xkjT009).

  • ↵*H.S. and X.G. contributed equally to this work.

Funding

  • National natural science foundation of china

    81870413
  • Scientific Research Promotion Plan of Anhui Medical University

    2022xkjT009
  • Anhui Province Postgraduate Education Quality Project

    2023xscx050

Other Version

  • You are viewing the most recent version of this article.
  • previous version (December 03, 2024).

Online Impact

 

Article usage

Select a custom date range for the past year
E.g., 2026-02-14
to
E.g., 2026-02-14

Article usage: December 2024 to February 2026

AbstractFullPdf
Dec 2024437506376
Total 2024437506376
Jan 202566266144
Feb 202529235121
Mar 20252321886
Apr 20251016958
May 20251115352
Jun 20251727357
Jul 2025920948
Aug 20251614137
Sep 20251023753
Oct 20251316769
Nov 20252521142
Dec 20251622855
Total 20252452507822
Jan 20261123755
Feb 2026517316
Total 20261641071
Total69834231269
Back to top

In this issue

eneuro: 11 (12)
eNeuro
Vol. 11, Issue 12
December 2024
  • Table of Contents
  • Index by author
  • Masthead (PDF)
Email

Thank you for sharing this eNeuro article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
AD-Like Neuropsychiatric Dysfunction in a Mice Model Induced by a Combination of High-Fat Diet and Intraperitoneal Injection of Streptozotocin
(Your Name) has forwarded a page to you from eNeuro
(Your Name) thought you would be interested in this article in eNeuro.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
AD-Like Neuropsychiatric Dysfunction in a Mice Model Induced by a Combination of High-Fat Diet and Intraperitoneal Injection of Streptozotocin
Huaizhi Sun, Xinran Gao, Jiachun Niu, Pengquan Chen, Shuai He, Songlin Xu, Jinfang Ge
eNeuro 3 December 2024, 11 (12) ENEURO.0310-24.2024; DOI: 10.1523/ENEURO.0310-24.2024

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Share
AD-Like Neuropsychiatric Dysfunction in a Mice Model Induced by a Combination of High-Fat Diet and Intraperitoneal Injection of Streptozotocin
Huaizhi Sun, Xinran Gao, Jiachun Niu, Pengquan Chen, Shuai He, Songlin Xu, Jinfang Ge
eNeuro 3 December 2024, 11 (12) ENEURO.0310-24.2024; DOI: 10.1523/ENEURO.0310-24.2024
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Significance Statement
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Footnotes
    • References
    • Synthesis
    • Author Response
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • AD
  • cognitive function
  • microglia
  • neuroinflammation
  • TREM1/2

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

Research Article: New Research

  • Sensory-cell population integrity required to preserve minimal and normal vestibulo-ocular reflexes reveals the critical role of type I hair cells in canal- and otolith-specific functions
  • Galanin inhibits histaminergic neurons via galanin receptor 1
  • sAPPα inhibits neurite outgrowth in primary mouse neurons via GABA B Receptor subunit 1a
Show more Research Article: New Research

Cognition and Behavior

  • The Novel Progressive Ratio with Reset Task Reveals Adaptive Effort-Delay Trade-Offs
  • TriNet-MTL: A Multi-Branch Deep Learning Framework for Biometric Identification and Cognitive State Inference from Auditory-Evoked EEG
  • When Familiar Faces Feel Better: A Framework for Social Neurocognitive Aging in a Rat Model
Show more Cognition and Behavior

Subjects

  • Cognition and Behavior
  • Home
  • Alerts
  • Follow SFN on BlueSky
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Latest Articles
  • Issue Archive
  • Blog
  • Browse by Topic

Information

  • For Authors
  • For the Media

About

  • About the Journal
  • Editorial Board
  • Privacy Notice
  • Contact
  • Feedback
(eNeuro logo)
(SfN logo)

Copyright © 2026 by the Society for Neuroscience.
eNeuro eISSN: 2373-2822

The ideas and opinions expressed in eNeuro do not necessarily reflect those of SfN or the eNeuro Editorial Board. Publication of an advertisement or other product mention in eNeuro should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in eNeuro.