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Research ArticleResearch Article: New Research, Disorders of the Nervous System

CLEC5A Promotes Neuronal Pyroptosis in Rat Spinal Cord Injury Models by Interacting with TREM1 and Elevating NLRC4 Expression

Yonghong Tan, Qiong Wang, Yubing Guo, Na Zhang, Yingyi Xu, Xue Bai, Jianhua Liu and Xiaobao Bi
eNeuro 26 August 2024, 11 (10) ENEURO.0111-24.2024; https://doi.org/10.1523/ENEURO.0111-24.2024
Yonghong Tan
Department of Anesthesiology, Guangzhou Women and Children’s Medical Center, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou 510623, China
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Qiong Wang
Department of Anesthesiology, Guangzhou Women and Children’s Medical Center, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou 510623, China
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Yubing Guo
Department of Anesthesiology, Guangzhou Women and Children’s Medical Center, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou 510623, China
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Na Zhang
Department of Anesthesiology, Guangzhou Women and Children’s Medical Center, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou 510623, China
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Yingyi Xu
Department of Anesthesiology, Guangzhou Women and Children’s Medical Center, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou 510623, China
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Xue Bai
Department of Anesthesiology, Guangzhou Women and Children’s Medical Center, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou 510623, China
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Jianhua Liu
Department of Anesthesiology, Guangzhou Women and Children’s Medical Center, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou 510623, China
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Xiaobao Bi
Department of Anesthesiology, Guangzhou Women and Children’s Medical Center, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou 510623, China
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0111-24.2024
PubMed 
39187376
Published By 
Society for Neuroscience
History 
  • Received March 13, 2024
  • Revision received June 17, 2024
  • Accepted August 1, 2024
  • Published online August 26, 2024.
Copyright & Usage 
Copyright © 2024 Tan et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Yonghong Tan*,
  2. Qiong Wang*,
  3. Yubing Guo,
  4. Na Zhang,
  5. Yingyi Xu,
  6. Xue Bai,
  7. Jianhua Liu and
  8. Xiaobao Bi
  1. Department of Anesthesiology, Guangzhou Women and Children’s Medical Center, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou 510623, China
  1. Correspondence should be addressed to Xiaobao Bi at bobjuan{at}sina.cn.
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Author contributions

  1. Author contributions: Y.G. designed research; Xiaobao Bi performed research; N.Z. contributed unpublished reagents/analytic tools; Y.X., Xue Bai, and J.L. analyzed data; Y.T. and Q.W. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by Guangzhou Municipal Science and Technology Project (NO. 202102080031).

  • ↵*Y.T. and Q.W. contributed equally to this work.

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CLEC5A Promotes Neuronal Pyroptosis in Rat Spinal Cord Injury Models by Interacting with TREM1 and Elevating NLRC4 Expression
Yonghong Tan, Qiong Wang, Yubing Guo, Na Zhang, Yingyi Xu, Xue Bai, Jianhua Liu, Xiaobao Bi
eNeuro 26 August 2024, 11 (10) ENEURO.0111-24.2024; DOI: 10.1523/ENEURO.0111-24.2024

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CLEC5A Promotes Neuronal Pyroptosis in Rat Spinal Cord Injury Models by Interacting with TREM1 and Elevating NLRC4 Expression
Yonghong Tan, Qiong Wang, Yubing Guo, Na Zhang, Yingyi Xu, Xue Bai, Jianhua Liu, Xiaobao Bi
eNeuro 26 August 2024, 11 (10) ENEURO.0111-24.2024; DOI: 10.1523/ENEURO.0111-24.2024
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Keywords

  • CLEC5A
  • NLRC4
  • neuronal pyroptosis
  • spinal cord injury
  • TREM1

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