Article Information
- Received December 15, 2023
- Revision received September 4, 2024
- Accepted September 9, 2024
- Published online September 12, 2024.
Author Information
- Zac Bowen1,2,*,
- Dulara De Zoysa1,3,*,
- Kelson Shilling-Scrivo4,5,
- Samira Aghayee1,
- Giorgio Di Salvo6,
- Aleksandr Smirnov1,7,
- Patrick O. Kanold5,6,7 and
- Wolfgang Losert1
- 1Institute for Physical Science and Technology, University of Maryland, College Park, Maryland 20742
- 2Fraunhofer USA Center Mid-Atlantic, Riverdale, Maryland 20737
- 3Fischell Department of Bioengineering, University of Maryland, College Park, Maryland 20742
- 4Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland 21230
- 5Department of Biology, University of Maryland, College Park, Maryland 20742
- 6Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 20215
- 7Kavli NDI, Johns Hopkins University, Baltimore, Maryland 20215
- Correspondence should be addressed to Wolfgang Losert at wlosert{at}umd.edu.
Author contributions
Author contributions: P.O.K. and W.L. designed research; Z.B., D.D.Z., K.S.-S., S.A., G.D.S., and A.S. performed research; K.S.-S., S.A., P.O.K., and W.L. contributed unpublished reagents/analytic tools; Z.B., D.D.Z., G.D.S., and A.S. analyzed data; Z.B., D.D.Z., K.S.-S., S.A., A.S., P.O.K., and W.L. wrote the paper.
Disclosures
The authors declare no competing financial interests.
We thank Daniel Winkowski and Samuel Potter for their code contributions to early versions of the software. We thank Aminah Sheikh and Jonah Mittelstadt for testing the early versions of the application. We also thank Dr. Kate M. O’Neill for her valuable feedback on the manuscript and Gioula Kalapotharakou for annotating and modularizing the MATLAB codes.
This work was funded by the National Institutes of Health, USA BRAIN initiative grant, 1U19NS107464. NeuroART: Real-time analysis and targeting of neuronal population activity during calcium imaging for informed closed-loop experiments.
↵*Z.B. and D.D.Z. contributed equally to this work.
Funding
NIH BRAIN Initiative
1U19NS107464
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