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Research ArticleResearch Article: Methods/New Tools, Neuronal Excitability

SimplyFire: An Open-Source, Customizable Software Application for the Analysis of Synaptic Events

Megumi Mori, Andrew Rosko, Jill Farnsworth, Guadalupe Carrasco, Parisa Broomandkhoshbacht, Kristeen Pareja-Navarro and A. Pejmun Haghighi
eNeuro 2 January 2024, 11 (1) ENEURO.0326-23.2023; https://doi.org/10.1523/ENEURO.0326-23.2023
Megumi Mori
1The Buck Institute for Research on Aging, Novato 94947, California
2Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco 94158, California
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Andrew Rosko
1The Buck Institute for Research on Aging, Novato 94947, California
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Jill Farnsworth
1The Buck Institute for Research on Aging, Novato 94947, California
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Guadalupe Carrasco
1The Buck Institute for Research on Aging, Novato 94947, California
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Parisa Broomandkhoshbacht
1The Buck Institute for Research on Aging, Novato 94947, California
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Kristeen Pareja-Navarro
1The Buck Institute for Research on Aging, Novato 94947, California
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A. Pejmun Haghighi
1The Buck Institute for Research on Aging, Novato 94947, California
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0326-23.2023
PubMed 
38167616
Published By 
Society for Neuroscience
History 
  • Received August 26, 2023
  • Revision received November 30, 2023
  • Accepted December 21, 2023
  • Published online January 2, 2024.
Copyright & Usage 
Copyright © 2024 Mori et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Megumi Mori1,2,*,
  2. Andrew Rosko1,*,
  3. Jill Farnsworth1,
  4. Guadalupe Carrasco1,
  5. Parisa Broomandkhoshbacht1,
  6. Kristeen Pareja-Navarro1 and
  7. A. Pejmun Haghighi1
  1. 1The Buck Institute for Research on Aging, Novato 94947, California
  2. 2Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco 94158, California
  1. Correspondence should be addressed to A. Pejmun Haghighi at phaghighi{at}buckinstitute.org.
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Author contributions

  1. Author contributions: M.M., A.R., and A.P.H. designed research; M.M., A.R., J.F., G.C., and K.P.-N. performed research; M.M., A.R., J.F., and P.B. analyzed data; M.M., A.R., and A.P.H. wrote the paper.

Disclosures

  • The authors report no conflict of interest.

  • We thank the members of the Haghighi Lab for their support, in particular, Olfat Malak for discussions and Myriam Mujahidine for technical support. We thank the Bloomington Stock Center for fly stocks. We would also like to thank Dr. Tara Tracy for support with human iPSC-derived neurons and useful discussions. J.F. was a recipient of a T32 postdoctoral fellowship. This work was funded by the NIH grant R01NS082793 provided to A.P.H.

  • ↵* M.M. and A.R. contributed equally to this work.

Funding

  • HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)

    NS082793
  • NIH Fellowship

    T32

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  • You are viewing the most recent version of this article.
  • previous version (January 02, 2024).

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SimplyFire: An Open-Source, Customizable Software Application for the Analysis of Synaptic Events
Megumi Mori, Andrew Rosko, Jill Farnsworth, Guadalupe Carrasco, Parisa Broomandkhoshbacht, Kristeen Pareja-Navarro, A. Pejmun Haghighi
eNeuro 2 January 2024, 11 (1) ENEURO.0326-23.2023; DOI: 10.1523/ENEURO.0326-23.2023

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SimplyFire: An Open-Source, Customizable Software Application for the Analysis of Synaptic Events
Megumi Mori, Andrew Rosko, Jill Farnsworth, Guadalupe Carrasco, Parisa Broomandkhoshbacht, Kristeen Pareja-Navarro, A. Pejmun Haghighi
eNeuro 2 January 2024, 11 (1) ENEURO.0326-23.2023; DOI: 10.1523/ENEURO.0326-23.2023
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Keywords

  • data analysis
  • electrophysiology
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  • synaptic events

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