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Research ArticleOpen Source Tools and Methods, Novel Tools and Methods

Chronic, Reusable, Multiday Neuropixels Recordings during Free-Moving Operant Behavior

Zhimin Song, Abigail Alpers, Kasey Warner, Francesca Iacobucci, Eric Hoskins, John F. Disterhoft, Joel L. Voss and Alik S. Widge
eNeuro 22 January 2024, 11 (1) ENEURO.0245-23.2023; https://doi.org/10.1523/ENEURO.0245-23.2023
Zhimin Song
1Department of Psychiatry, University of Minnesota, Minneapolis, 55455 Minnesota
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  • For correspondence: song0528{at}umn.edu
Abigail Alpers
1Department of Psychiatry, University of Minnesota, Minneapolis, 55455 Minnesota
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Kasey Warner
1Department of Psychiatry, University of Minnesota, Minneapolis, 55455 Minnesota
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Francesca Iacobucci
1Department of Psychiatry, University of Minnesota, Minneapolis, 55455 Minnesota
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Eric Hoskins
1Department of Psychiatry, University of Minnesota, Minneapolis, 55455 Minnesota
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  • ORCID record for Eric Hoskins
John F. Disterhoft
2Department of Neuroscience, Northwestern University, Evanston, 60208 Illinois
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Joel L. Voss
3Department of Neurology, University of Chicago, Chicago, 60637 Illinois
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Alik S. Widge
1Department of Psychiatry, University of Minnesota, Minneapolis, 55455 Minnesota
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0245-23.2023
PubMed 
38253540
Published By 
Society for Neuroscience
History 
  • Received June 28, 2023
  • Revision received December 13, 2023
  • Accepted December 17, 2023
  • Published online January 22, 2024.
Copyright & Usage 
Copyright © 2024 Song et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Zhimin Song1⇑,
  2. Abigail Alpers1,
  3. Kasey Warner1,
  4. Francesca Iacobucci1,
  5. Eric Hoskins1,
  6. John F. Disterhoft2,
  7. Joel L. Voss3 and
  8. Alik S. Widge1
  1. 1Department of Psychiatry, University of Minnesota, Minneapolis, 55455 Minnesota
  2. 2Department of Neuroscience, Northwestern University, Evanston, 60208 Illinois
  3. 3Department of Neurology, University of Chicago, Chicago, 60637 Illinois
  1. Correspondence should be addressed to Zhimin Song at song0528{at}umn.edu.
View Full Text

Author contributions

  1. Author contributions: Z.S., A.A., K.W., F.I., J.F.D., J.L.V., and A.S.W. designed research; Z.S., A.A., K.W., F.I., and E.H. performed research; Z.S., K.W., and E.H. analyzed data; Z.S., A.A., F.I., and A.S.W. wrote the paper.

Disclosures

  • The authors report no conflict of interest.

  • The work was supported by NIH R01NS113804, R01NS120851, and the Medical Discovery Team on Addictions at the University of Minnesota. The authors acknowledge and are grateful for helpful tips from Dr. Thomas Luo at Princeton University via emails. We are thankful to Megan Mensinger for editing the manuscript and Makayla Cizek for creating Neuropixels 2.0 stl files.

Funding

  • NIH

    R01NS113804
  • NIH

    R01NS120851

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AbstractFullPdf
Jan 2024442562179
Feb 2024361266129
Mar 20246414467
Apr 20247013366
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Chronic, Reusable, Multiday Neuropixels Recordings during Free-Moving Operant Behavior
Zhimin Song, Abigail Alpers, Kasey Warner, Francesca Iacobucci, Eric Hoskins, John F. Disterhoft, Joel L. Voss, Alik S. Widge
eNeuro 22 January 2024, 11 (1) ENEURO.0245-23.2023; DOI: 10.1523/ENEURO.0245-23.2023

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Chronic, Reusable, Multiday Neuropixels Recordings during Free-Moving Operant Behavior
Zhimin Song, Abigail Alpers, Kasey Warner, Francesca Iacobucci, Eric Hoskins, John F. Disterhoft, Joel L. Voss, Alik S. Widge
eNeuro 22 January 2024, 11 (1) ENEURO.0245-23.2023; DOI: 10.1523/ENEURO.0245-23.2023
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Keywords

  • cognitive flexibility
  • deep brain stimulation
  • paired associate learning
  • set shift

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