Article Information
- Received March 5, 2023
- Revision received October 10, 2023
- Accepted November 6, 2023
- Published online December 27, 2023.
Author Information
- Arlene J. George1,2,
- Wei Wei1,2,
- Dhanya N. Pyaram1,2,
- Morgan Gomez1,
- Nitheyaa Shree1,
- Jayashree Kadirvelu1,
- Hannah Lail3,
- Desiree Wanders3,
- Anne Z. Murphy1 and
- Angela M. Mabb1,2
- 1Neuroscience Institute, Georgia State University, Atlanta 30302, Georgia
- 2Center for Behavioral Neuroscience, Georgia State University, Atlanta 30303, Georgia
- 3Department of Nutrition, Georgia State University, Atlanta 30303, Georgia
- Correspondence should be addressed to Angela M. Mabb at amabb{at}gsu.edu.
Author contributions
Author contributions: A.J.G., W.W., D.W., and A.M.M. designed research; A.J.G., W.W., D.N.P., M.G., N.S., J.K., H.L., and A.M.M. performed research; D.W. contributed unpublished reagents/analytic tools; A.J.G., W.W., D.N.P., M.G., and H.L. analyzed data; A.J.G., W.W., D.N.P., D.W., A.Z.M., and A.M.M. wrote the paper.
Disclosures
The authors declare no competing financial interests.
We acknowledge Zachary Allen, for assistance in the development, genotyping, and maintenance of the Rnf216 KO mice and Hannah Harder for guidance and sharing code for statistical analysis of microglia. This work was funded by the National Institute of Neurological Disorders and Stroke (grant R21NS116760) and National Science Foundation Career Award (2047700), National Ataxia Foundation Young Investigator Research Grant, the Cleon C. Arrington Research Initiation Grant Program (RIG-93), and a Molecular Basis of Disease Seed Grant to A.M.M.; A.Z.M. is funded by the National Institutes of Health (DA041529); A.J.G., M.G., and H.L. were funded by the Brains & Behavior Fellowship. A.J.G. was funded by the Kenneth W. and Georganne F. Honeycutt Fellowship.
Funding
NIH/NINDS
R21NS116760National Ataxia Foundation Young Investigator Research Grant
Cleon C. Arrington Research Initiation Grant Program
RIG-93Molecular Basis of Disease Grant
NIH
DA041529Brains & Behavior Fellowship
Kenneth W. and Georganne F. Honeycutt Fellowship
National Science Foundation (NSF)
2047700
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