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Research ArticleResearch Article: New Research, Sensory and Motor Systems

The Antiarrhythmic Drug Flecainide Enhances Aversion to HCl in Mice

Yuko Kawabata, Shingo Takai, Keisuke Sanematsu, Ryusuke Yoshida, Fuminori Kawabata and Noriatsu Shigemura
eNeuro 11 September 2023, 10 (9) ENEURO.0048-23.2023; https://doi.org/10.1523/ENEURO.0048-23.2023
Yuko Kawabata
1Section of Oral Neuroscience, Graduate School of Dental Science, Kyushu University, Fukuoka 812-8582, Japan
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Shingo Takai
1Section of Oral Neuroscience, Graduate School of Dental Science, Kyushu University, Fukuoka 812-8582, Japan
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Keisuke Sanematsu
1Section of Oral Neuroscience, Graduate School of Dental Science, Kyushu University, Fukuoka 812-8582, Japan
2Research and Development Center for Five-Sense Devices, Kyushu University, Fukuoka 819-0395, Japan
5Oral Health/Brain Health/Total Health Research Center, Graduate School of Dental Science, Kyushu University, Fukuoka 812-8582, Japan
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Ryusuke Yoshida
3Department of Oral Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8525, Japan
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Fuminori Kawabata
4Physiology of Domestic Animals, Faculty of Agriculture and Life Science, Hirosaki University, Hirosaki 036-8561, Japan
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Noriatsu Shigemura
1Section of Oral Neuroscience, Graduate School of Dental Science, Kyushu University, Fukuoka 812-8582, Japan
2Research and Development Center for Five-Sense Devices, Kyushu University, Fukuoka 819-0395, Japan
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0048-23.2023
PubMed 
37696662
Published By 
Society for Neuroscience
History 
  • Received February 9, 2023
  • Revision received August 21, 2023
  • Accepted September 4, 2023
  • Published online September 11, 2023.
Copyright & Usage 
Copyright © 2023 Kawabata et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Yuko Kawabata1,
  2. Shingo Takai1,
  3. Keisuke Sanematsu1,2,5,
  4. Ryusuke Yoshida3,
  5. Fuminori Kawabata4 and
  6. Noriatsu Shigemura1,2
  1. 1Section of Oral Neuroscience, Graduate School of Dental Science, Kyushu University, Fukuoka 812-8582, Japan
  2. 2Research and Development Center for Five-Sense Devices, Kyushu University, Fukuoka 819-0395, Japan
  3. 3Department of Oral Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8525, Japan
  4. 4Physiology of Domestic Animals, Faculty of Agriculture and Life Science, Hirosaki University, Hirosaki 036-8561, Japan
  5. 5Oral Health/Brain Health/Total Health Research Center, Graduate School of Dental Science, Kyushu University, Fukuoka 812-8582, Japan
  1. Correspondence should be addressed to Noriatsu Shigemura at shigemura{at}dent.kyushu-u.ac.jp.
View Full Text

Author contributions

  1. Author contributions: Y.K., S.T., and N.S. designed research; Y.K. performed research; S.T., R.Y., and F.K. contributed unpublished reagents/analytic tools; Y.K., S.T., K.S., F.K., and N.S. analyzed data; Y.K., S.T., F.K., and N.S. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by JSPS KAKENHI Grants JP19H03818, JP18J20599, JP19KT0005, JP22K19672, and JP23K15979.

Funding

  • MEXT | Japan Society for the Promotion of Science (JSPS)

    JP19H03818; JP18J20599; JP19KT0005; JP22K19672

Other Version

  • You are viewing the most recent version of this article.
  • previous version (September 11, 2023).

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The Antiarrhythmic Drug Flecainide Enhances Aversion to HCl in Mice
Yuko Kawabata, Shingo Takai, Keisuke Sanematsu, Ryusuke Yoshida, Fuminori Kawabata, Noriatsu Shigemura
eNeuro 11 September 2023, 10 (9) ENEURO.0048-23.2023; DOI: 10.1523/ENEURO.0048-23.2023

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The Antiarrhythmic Drug Flecainide Enhances Aversion to HCl in Mice
Yuko Kawabata, Shingo Takai, Keisuke Sanematsu, Ryusuke Yoshida, Fuminori Kawabata, Noriatsu Shigemura
eNeuro 11 September 2023, 10 (9) ENEURO.0048-23.2023; DOI: 10.1523/ENEURO.0048-23.2023
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Keywords

  • antiarrhythmic drug
  • flecainide
  • taste
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