Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT

User menu

Search

  • Advanced search
eNeuro
eNeuro

Advanced Search

 

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT
PreviousNext
Research ArticleResearch Article: New Research, Sensory and Motor Systems

Reorganization of Corticospinal Projections after Prominent Recovery of Finger Dexterity from Partial Spinal Cord Injury in Macaque Monkeys

Masahiro Sawada, Kimika Yoshino-Saito, Taihei Ninomiya, Takao Oishi, Toshihide Yamashita, Hirotaka Onoe, Masahiko Takada, Yukio Nishimura and Tadashi Isa
eNeuro 19 July 2023, 10 (8) ENEURO.0209-23.2023; https://doi.org/10.1523/ENEURO.0209-23.2023
Masahiro Sawada
1Department of Developmental Physiology, National Institute for Physiological Sciences, Okazaki 444-8585, Japan
2Department of Neurosurgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Masahiro Sawada
Kimika Yoshino-Saito
1Department of Developmental Physiology, National Institute for Physiological Sciences, Okazaki 444-8585, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Taihei Ninomiya
3Systems Neuroscience, Primate Research Institute, Kyoto University, Inuyama 484-8506, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Takao Oishi
3Systems Neuroscience, Primate Research Institute, Kyoto University, Inuyama 484-8506, Japan
4Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama 332-0012, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Toshihide Yamashita
4Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama 332-0012, Japan
4Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama 332-0012, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Toshihide Yamashita
Hirotaka Onoe
6Human Brain Research Center, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Masahiko Takada
3Systems Neuroscience, Primate Research Institute, Kyoto University, Inuyama 484-8506, Japan
4Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama 332-0012, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yukio Nishimura
1Department of Developmental Physiology, National Institute for Physiological Sciences, Okazaki 444-8585, Japan
4Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama 332-0012, Japan
7Neural Prosthetics Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan
8The graduate University for Advanced Studies (SOKENDAI), Hayama 240-0193, Japan
9Precursory Research for Embryonic Science and Technology, Japan Science and Technology Agency, Saitama 332-0012, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Yukio Nishimura
Tadashi Isa
1Department of Developmental Physiology, National Institute for Physiological Sciences, Okazaki 444-8585, Japan
4Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama 332-0012, Japan
6Human Brain Research Center, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan
8The graduate University for Advanced Studies (SOKENDAI), Hayama 240-0193, Japan
10Department of Neuroscience, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan
11Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto 606-8501, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Tadashi Isa
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/ENEURO.0209-23.2023
PubMed 
37468328
Published By 
Society for Neuroscience
History 
  • Received June 19, 2023
  • Accepted July 11, 2023
  • Published online July 19, 2023.
Copyright & Usage 
Copyright © 2023 Sawada et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Masahiro Sawada1,2,
  2. Kimika Yoshino-Saito1,
  3. Taihei Ninomiya3,
  4. Takao Oishi3,4,
  5. Toshihide Yamashita4,5,
  6. Hirotaka Onoe6,
  7. Masahiko Takada3,4,
  8. Yukio Nishimura1,4,7,8,9 and
  9. Tadashi Isa1,4,6,8,10,11
  1. 1Department of Developmental Physiology, National Institute for Physiological Sciences, Okazaki 444-8585, Japan
  2. 2Department of Neurosurgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan
  3. 3Systems Neuroscience, Primate Research Institute, Kyoto University, Inuyama 484-8506, Japan
  4. 4Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama 332-0012, Japan
  5. 5Department of Molecular Neuroscience, Graduate School Medicine, Osaka University, Suita 565-0871, Japan
  6. 6Human Brain Research Center, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan
  7. 7Neural Prosthetics Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan
  8. 8The graduate University for Advanced Studies (SOKENDAI), Hayama 240-0193, Japan
  9. 9Precursory Research for Embryonic Science and Technology, Japan Science and Technology Agency, Saitama 332-0012, Japan
  10. 10Department of Neuroscience, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan
  11. 11Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto 606-8501, Japan
  1. Correspondence should be addressed to Tadashi Isa at isa.tadashi.7u{at}kyoto-u.ac.jp or Yukio Nishimura at nishimura-yk{at}igakuken.or.jp.
  • M. Sawada’s present address: Department of Neurosurgery, Tazuke Kofukai Medical Research Institute and Kitano Hospital, Osaka 603-8333, Japan.

  • K. Yoshino-Saito’s present address: Department of Agro-Environmental Sciences, Graduate School of Bioresources and Bioenvironmental Sciences, Kyushu University, Fukuoka 819-0395, Japan.

View Full Text

Author contributions

  1. Author contributions: M.S., K.Y.-S., and Y.N. performed research; H.O., Y.N., and T.I. designed research; M.S., K.Y.-S., T.N., Y.N., and T.I. analyzed data; M.S., K.Y.-S., T.N., T.O., T.Y., H.O., M.T., Y.N., and T.I. wrote the paper.

  • M. Sawada’s present address: Department of Neurosurgery, Tazuke Kofukai Medical Research Institute and Kitano Hospital, Osaka 603-8333, Japan.

  • K. Yoshino-Saito’s present address: Department of Agro-Environmental Sciences, Graduate School of Bioresources and Bioenvironmental Sciences, Kyushu University, Fukuoka 819-0395, Japan.

View Abstract

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by grants from the “Brain Machine Interface Development” and performed under the Strategic Research Program for Brain Sciences from Ministry of Education, Culture, Sports, Science, and Technology (MEXT) and the Japan Agency for Medical Research and Development (Y.N.), Grant-in-Aid for Scientific Research on Innovative Areas “Adaptive circuit shift” Project nos. 26112008 (to T.I.) and 26112003 (to H.O.), and Grants-in-Aid for Scientific Research from MEXT KAKENHI (B) no. 24300196 and (A) no.15H01819 (to H.O.).

Funding

  • MEXT 

  • Japan Agency for Medical Research and Development (AMED)

  • Grant-in-aid for Scientific Research on Innovative Areas "Adaptive circuit shift"

    26112008; 26112003
  • Grant-in-Aid for Scientific Research from MEXT

    24300196; 15H01819

Other Version

  • You are viewing the most recent version of this article.
  • previous version (July 19, 2023).

Online Impact

 

Article usage

Select a custom date range for the past year
E.g., 2026-01-16
to
E.g., 2026-01-16

Article usage: July 2023 to January 2026

AbstractFullPdf
Jul 20232730101
Aug 2023121246117
Sep 20233214640
Oct 20231714950
Nov 2023510624
Dec 20231012225
Total 2023458769357
Jan 2024912450
Feb 2024310530
Mar 202479723
Apr 20241210828
May 2024149824
Jun 2024109442
Jul 2024510128
Aug 2024179425
Sep 2024710632
Oct 202428619
Nov 202439411
Dec 202418420
Total 2024901191332
Jan 20251110331
Feb 2025410814
Mar 2025514216
Apr 2025611114
May 2025410416
Jun 20251712333
Jul 20251212629
Aug 202579823
Sep 20252114420
Oct 20252613425
Nov 20251514427
Dec 2025416744
Total 20251321504292
Jan 20265665
Total 20265665
Total6853530986
Back to top

In this issue

eneuro: 10 (8)
eNeuro
Vol. 10, Issue 8
August 2023
  • Table of Contents
  • Index by author
  • Masthead (PDF)
Email

Thank you for sharing this eNeuro article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Reorganization of Corticospinal Projections after Prominent Recovery of Finger Dexterity from Partial Spinal Cord Injury in Macaque Monkeys
(Your Name) has forwarded a page to you from eNeuro
(Your Name) thought you would be interested in this article in eNeuro.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
Reorganization of Corticospinal Projections after Prominent Recovery of Finger Dexterity from Partial Spinal Cord Injury in Macaque Monkeys
Masahiro Sawada, Kimika Yoshino-Saito, Taihei Ninomiya, Takao Oishi, Toshihide Yamashita, Hirotaka Onoe, Masahiko Takada, Yukio Nishimura, Tadashi Isa
eNeuro 19 July 2023, 10 (8) ENEURO.0209-23.2023; DOI: 10.1523/ENEURO.0209-23.2023

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Share
Reorganization of Corticospinal Projections after Prominent Recovery of Finger Dexterity from Partial Spinal Cord Injury in Macaque Monkeys
Masahiro Sawada, Kimika Yoshino-Saito, Taihei Ninomiya, Takao Oishi, Toshihide Yamashita, Hirotaka Onoe, Masahiko Takada, Yukio Nishimura, Tadashi Isa
eNeuro 19 July 2023, 10 (8) ENEURO.0209-23.2023; DOI: 10.1523/ENEURO.0209-23.2023
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Significance Statement
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments
    • Footnotes
    • References
    • Synthesis
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • spinal cord injury
  • finger dexterity
  • corticospinal tract
  • functional recovery
  • sprouting
  • primate

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

Research Article: New Research

  • Independent encoding of orientation and mean luminance by mouse visual cortex
  • Neck Vascular Biomechanical Dysfunction Precedes Brain Biochemical Alterations in a Murine Model of Alzheimer’s Disease
  • Alpha-2 Adrenergic Agonists Reduce Heavy Alcohol Drinking and Improve Cognitive Performance in Mice
Show more Research Article: New Research

Sensory and Motor Systems

  • Independent encoding of orientation and mean luminance by mouse visual cortex
  • Neck Vascular Biomechanical Dysfunction Precedes Brain Biochemical Alterations in a Murine Model of Alzheimer’s Disease
  • Alpha-2 Adrenergic Agonists Reduce Heavy Alcohol Drinking and Improve Cognitive Performance in Mice
Show more Sensory and Motor Systems

Subjects

  • Sensory and Motor Systems
  • Home
  • Alerts
  • Follow SFN on BlueSky
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Latest Articles
  • Issue Archive
  • Blog
  • Browse by Topic

Information

  • For Authors
  • For the Media

About

  • About the Journal
  • Editorial Board
  • Privacy Notice
  • Contact
  • Feedback
(eNeuro logo)
(SfN logo)

Copyright © 2026 by the Society for Neuroscience.
eNeuro eISSN: 2373-2822

The ideas and opinions expressed in eNeuro do not necessarily reflect those of SfN or the eNeuro Editorial Board. Publication of an advertisement or other product mention in eNeuro should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in eNeuro.