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Research ArticleResearch Article: New Research, Cognition and Behavior

Neuronal Representation of a Working Memory-Based Decision Strategy in the Motor and Prefrontal Cortico-Basal Ganglia Loops

Tomohiko Yoshizawa, Makoto Ito and Kenji Doya
eNeuro 1 June 2023, 10 (6) ENEURO.0413-22.2023; https://doi.org/10.1523/ENEURO.0413-22.2023
Tomohiko Yoshizawa
1Oral Physiology, Department of Oral Functional Science, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo 060-8586, Japan
2Neural Computation Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0412, Japan
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Makoto Ito
2Neural Computation Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0412, Japan
3LiNKX, Inc, Tokyo 105-0003, Japan
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Kenji Doya
2Neural Computation Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0412, Japan
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0413-22.2023
PubMed 
37263790
Published By 
Society for Neuroscience
History 
  • Received October 4, 2022
  • Revision received May 15, 2023
  • Accepted May 18, 2023
  • Published online June 1, 2023.
Copyright & Usage 
Copyright © 2023 Yoshizawa et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Tomohiko Yoshizawa1,2,
  2. Makoto Ito2,3 and
  3. Kenji Doya2
  1. 1Oral Physiology, Department of Oral Functional Science, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo 060-8586, Japan
  2. 2Neural Computation Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0412, Japan
  3. 3LiNKX, Inc, Tokyo 105-0003, Japan
  1. Correspondence should be addressed to Tomohiko Yoshizawa at yoshizawa{at}den.hokudai.ac.jp or Kenji Doya at doya{at}oist.jp.
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Author contributions

  1. Author contributions: T.Y., M.I., and K.D. designed research; T.Y. and M.I. performed research; T.Y. and M.I. contributed unpublished reagents/analytic tools; T.Y. and M.I. analyzed data; T.Y., M.I., and K.D. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by JSPS KAKENHI Grant Numbers JP16H06563 and JP23120007 (to K.D.) and JP19K16299 and JP22K15217 (to T.Y.) and the generous research support of Okinawa Institute of Science and Technology Graduate University for the Neural Computation Unit.

Funding

  • MEXT | Japan Society for the Promotion of Science (JSPS)

    JP16H06563; JP23120007; JP19K16299; JP22K15217

Other Version

  • You are viewing the most recent version of this article.
  • previous version (June 01, 2023).

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Jun 2023410204176
Jul 20234422970
Aug 20231916929
Sep 20232231868
Oct 20231724657
Nov 20231612628
Dec 20231012920
Total 20235381421448
Jan 20241711134
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Feb 202599910
Mar 2025610116
Apr 202578814
May 202589825
Jun 20251310019
Jul 20251011235
Aug 202569832
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Total 20251211313281
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Total 20266486
Total7863992946
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eneuro: 10 (6)
eNeuro
Vol. 10, Issue 6
June 2023
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Neuronal Representation of a Working Memory-Based Decision Strategy in the Motor and Prefrontal Cortico-Basal Ganglia Loops
Tomohiko Yoshizawa, Makoto Ito, Kenji Doya
eNeuro 1 June 2023, 10 (6) ENEURO.0413-22.2023; DOI: 10.1523/ENEURO.0413-22.2023

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Neuronal Representation of a Working Memory-Based Decision Strategy in the Motor and Prefrontal Cortico-Basal Ganglia Loops
Tomohiko Yoshizawa, Makoto Ito, Kenji Doya
eNeuro 1 June 2023, 10 (6) ENEURO.0413-22.2023; DOI: 10.1523/ENEURO.0413-22.2023
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Keywords

  • basal ganglia
  • motor cortex
  • prefrontal cortex
  • reinforcement learning
  • striatum
  • working memory

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