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Research ArticleResearch Article: Confirmation, Disorders of the Nervous System

Glycolytic System in Axons Supplement Decreased ATP Levels after Axotomy of the Peripheral Nerve

Tomofumi Takenaka, Yuichiro Ohnishi, Masamichi Yamamoto, Daiki Setoyama and Haruhiko Kishima
eNeuro 9 March 2023, 10 (3) ENEURO.0353-22.2023; DOI: https://doi.org/10.1523/ENEURO.0353-22.2023
Tomofumi Takenaka
1Department of neurosurgery, Graduate School of Medicine, Osaka University, Osaka, 565-0871, Japan
2Department of Research Promotion and Management, National Cerebral and Cardiovascular Center, Osaka, 564-8565, Japan
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Yuichiro Ohnishi
2Department of Research Promotion and Management, National Cerebral and Cardiovascular Center, Osaka, 564-8565, Japan
3Department of Neurosurgery, Osaka Gyoumeikan Hospital, Osaka, 554-0012, Japan
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Masamichi Yamamoto
2Department of Research Promotion and Management, National Cerebral and Cardiovascular Center, Osaka, 564-8565, Japan
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Daiki Setoyama
4Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan
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Haruhiko Kishima
1Department of neurosurgery, Graduate School of Medicine, Osaka University, Osaka, 565-0871, Japan
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0353-22.2023
PubMed 
36894321
Published By 
Society for Neuroscience
History 
  • Received August 30, 2022
  • Revision received February 4, 2023
  • Accepted February 25, 2023
  • Published online March 9, 2023.
Copyright & Usage 
Copyright © 2023 Takenaka et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Tomofumi Takenaka1,2,
  2. Yuichiro Ohnishi2,3,
  3. Masamichi Yamamoto2,
  4. Daiki Setoyama4 and
  5. Haruhiko Kishima1
  1. 1Department of neurosurgery, Graduate School of Medicine, Osaka University, Osaka, 565-0871, Japan
  2. 2Department of Research Promotion and Management, National Cerebral and Cardiovascular Center, Osaka, 564-8565, Japan
  3. 3Department of Neurosurgery, Osaka Gyoumeikan Hospital, Osaka, 554-0012, Japan
  4. 4Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan
  1. Correspondence should be addressed to Yuichiro Ohnishi at ohnishinsurg{at}gmail.com or Haruhiko Kishima at hkishima{at}nsurg.med.osaka-u.ac.jp.
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Author contributions

  1. Author contributions: T.T. and Y.O. designed research; T.T., Y.O., M.Y., and D.S. performed research; T.T. analyzed data; T.T., Y.O., and H.K. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the JSPS KAKENHI Grant Number JP 20K17967, the JSPS KAKENHI Grant Number 18H04085, and the AMED Grant Number JP20ek0610017.

Funding

  • MEXT | Japan Society for the Promotion of Science (JSPS)

    JP 20K17967; 18H04085
  • Japan Agency for Medical Research and Development (AMED)

    JP20ek0610017

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eneuro: 10 (3)
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March 2023
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Glycolytic System in Axons Supplement Decreased ATP Levels after Axotomy of the Peripheral Nerve
Tomofumi Takenaka, Yuichiro Ohnishi, Masamichi Yamamoto, Daiki Setoyama, Haruhiko Kishima
eNeuro 9 March 2023, 10 (3) ENEURO.0353-22.2023; DOI: 10.1523/ENEURO.0353-22.2023

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Glycolytic System in Axons Supplement Decreased ATP Levels after Axotomy of the Peripheral Nerve
Tomofumi Takenaka, Yuichiro Ohnishi, Masamichi Yamamoto, Daiki Setoyama, Haruhiko Kishima
eNeuro 9 March 2023, 10 (3) ENEURO.0353-22.2023; DOI: 10.1523/ENEURO.0353-22.2023
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Keywords

  • ATP
  • glycolytic system
  • in vivo imaging
  • mitochondria
  • Wallerian degeneration

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