Figure 2. Effect of the RhoF45L knock-in mutation on photoreceptor morphology. Representative images from retinas of three-, six-, and nine-month-old wild-type mice (A–C, respectively), and age-matched RhoF45L KI mice (D–F, respectively). Quantitative spider plots of ONL thickness as a function of distance from the optic nerve disk from wild-type mice (black; n = 4 each), and from RhoF45L KI mice (red; n = 5, 4, 5) measured at three-, six-, and nine-month time points (G–I, respectively). Quantitative spider plots of the number of photoreceptor nuclei per column in the ONL as a function of distance from the optic nerve disk from wild-type mice (black; n = 4 each), and from RhoF45L KI mice (red; n = 5, 4, 5) measured at three-, six-, and nine-month time points (J–L, respectively). Error bars indicate SEM; *p < 0.05.