Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT

User menu

Search

  • Advanced search
eNeuro
eNeuro

Advanced Search

 

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT
PreviousNext
Research ArticleResearch Article: New Research, Cognition and Behavior

The Role of GABA in the Dorsal Striatum-Raphe Nucleus Circuit Regulating Stress Vulnerability in Male Mice with High Levels of Shati/Nat8l

Hajime Miyanishi, Shiori Suga, Kazuyuki Sumi, Miho Takakuwa, Naotaka Izuo, Takashi Asano, Shin-ichi Muramatsu and Atsumi Nitta
eNeuro 9 October 2023, 10 (10) ENEURO.0162-23.2023; https://doi.org/10.1523/ENEURO.0162-23.2023
Hajime Miyanishi
1Department of Pharmaceutical Therapy and Neuropharmacology, Faculty of Pharmaceutical Sciences, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Shiori Suga
1Department of Pharmaceutical Therapy and Neuropharmacology, Faculty of Pharmaceutical Sciences, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kazuyuki Sumi
1Department of Pharmaceutical Therapy and Neuropharmacology, Faculty of Pharmaceutical Sciences, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Miho Takakuwa
1Department of Pharmaceutical Therapy and Neuropharmacology, Faculty of Pharmaceutical Sciences, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Naotaka Izuo
1Department of Pharmaceutical Therapy and Neuropharmacology, Faculty of Pharmaceutical Sciences, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Takashi Asano
1Department of Pharmaceutical Therapy and Neuropharmacology, Faculty of Pharmaceutical Sciences, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Shin-ichi Muramatsu
2Division of Neurological Gene Therapy, Center for Open Innovation, Jichi Medical University, Shimotsuke 329-0498, Japan
3Center for Gene & Cell Therapy, The Institute of Medical Science, The University of Tokyo, Tokyo 108-0071, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Atsumi Nitta
1Department of Pharmaceutical Therapy and Neuropharmacology, Faculty of Pharmaceutical Sciences, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Atsumi Nitta
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/ENEURO.0162-23.2023
PubMed 
37813564
Published By 
Society for Neuroscience
History 
  • Received May 16, 2023
  • Revision received September 26, 2023
  • Accepted October 1, 2023
  • Published online October 9, 2023.
Copyright & Usage 
Copyright © 2023 Miyanishi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Hajime Miyanishi1,
  2. Shiori Suga1,
  3. Kazuyuki Sumi1,
  4. Miho Takakuwa1,
  5. Naotaka Izuo1,
  6. Takashi Asano1,
  7. Shin-ichi Muramatsu2,3 and
  8. Atsumi Nitta1
  1. 1Department of Pharmaceutical Therapy and Neuropharmacology, Faculty of Pharmaceutical Sciences, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan
  2. 2Division of Neurological Gene Therapy, Center for Open Innovation, Jichi Medical University, Shimotsuke 329-0498, Japan
  3. 3Center for Gene & Cell Therapy, The Institute of Medical Science, The University of Tokyo, Tokyo 108-0071, Japan
  1. Correspondence should be addressed to Atsumi Nitta at nitta{at}pha.u-toyama.ac.jp.
View Full Text

Author contributions

  1. Author contributions: H.M. and A.N. designed research; H.M., S.S., K.S., and M.T. performed research; H.M. and S.-i.M. contributed unpublished reagents/analytic tools; H.M., N.I., and T.A. analyzed data; H.M. and A.N. wrote the paper.

Disclosures

  • S.-i.M. has equity with the Gene Therapy Research Institution, Co., Ltd., which commercializes AAV vectors for gene therapy applications. S.-i.M. has several conflicts of interest, to the extent that the work in this manuscript increases the value of these commercial holdings. All other authors declare no competing financial interests.

  • This work was supported by Japan Society for the Promotion of Science (JSPS) Grants-in-Aid for Scientific Research (KAKENHI) Grant Numbers JP22J11998 (to H.M.), 26293213 (to S.-i.M.), JP21H02632 (to A.N.), JP 22H04922, and JP 16H06276 (Grant-in-Aid for Scientific Research on Innovative Areas Platform for Advanced Technologies and Research Resources, Advanced Animal Model Support; AdAMS); Nishinomiya Basic Research Foundation (H.M.); Kobayashi Foundation (A.N.); and Smoking Research Foundation Grant for Biomedical Research and Foundation (A.N.). H.M. has been supported by the Nagai Memorial Research Scholarship from the Pharmaceutical Society of Japan.

Funding

  • MEXT | Japan Society for the Promotion of Science (JSPS)

    JP22J11998; 26293213; JP21H02632; JP 22H04922 (AdAMS); JP 16H06276 (AdAMS)
  • Nishinomiya Basic Research Foundation

  • Kobayashi Foundation

  • Smoking Research Foundation Grant for Biomedical Research and Foundation

Other Version

  • You are viewing the most recent version of this article.
  • previous version (October 09, 2023).

Online Impact

 

Article usage

Select a custom date range for the past year
E.g., 2026-01-14
to
E.g., 2026-01-14

Article usage: October 2023 to January 2026

AbstractFullPdf
Oct 2023396141185
Nov 20239115553
Dec 20235616760
Total 2023543463298
Jan 20245312032
Feb 20241612142
Mar 20241311833
Apr 20241810227
May 20241311634
Jun 20241311234
Jul 2024511529
Aug 2024139534
Sep 2024179827
Oct 202469829
Nov 202439531
Dec 2024510833
Total 20241751298385
Jan 202579339
Feb 2025611636
Mar 2025511130
Apr 20251010217
May 2025148820
Jun 2025149922
Jul 20251712249
Aug 20251211045
Sep 20251423927
Oct 20251611322
Nov 20252014552
Dec 20252217946
Total 20251571517405
Jan 2026124012
Total 2026124012
Total88733181100
Back to top

In this issue

eneuro: 10 (10)
eNeuro
Vol. 10, Issue 10
October 2023
  • Table of Contents
  • Index by author
  • Masthead (PDF)
Email

Thank you for sharing this eNeuro article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
The Role of GABA in the Dorsal Striatum-Raphe Nucleus Circuit Regulating Stress Vulnerability in Male Mice with High Levels of Shati/Nat8l
(Your Name) has forwarded a page to you from eNeuro
(Your Name) thought you would be interested in this article in eNeuro.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
The Role of GABA in the Dorsal Striatum-Raphe Nucleus Circuit Regulating Stress Vulnerability in Male Mice with High Levels of Shati/Nat8l
Hajime Miyanishi, Shiori Suga, Kazuyuki Sumi, Miho Takakuwa, Naotaka Izuo, Takashi Asano, Shin-ichi Muramatsu, Atsumi Nitta
eNeuro 9 October 2023, 10 (10) ENEURO.0162-23.2023; DOI: 10.1523/ENEURO.0162-23.2023

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Share
The Role of GABA in the Dorsal Striatum-Raphe Nucleus Circuit Regulating Stress Vulnerability in Male Mice with High Levels of Shati/Nat8l
Hajime Miyanishi, Shiori Suga, Kazuyuki Sumi, Miho Takakuwa, Naotaka Izuo, Takashi Asano, Shin-ichi Muramatsu, Atsumi Nitta
eNeuro 9 October 2023, 10 (10) ENEURO.0162-23.2023; DOI: 10.1523/ENEURO.0162-23.2023
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Significance Statement
    • Introduction
    • Materials and Methods
    • Result
    • Discussion
    • Acknowledgments
    • Footnotes
    • References
    • Synthesis
    • Author Response
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • 5-hydroxytryptamine
  • dorsal raphe nucleus
  • dorsal striatum
  • Shati/Nat8l
  • stress
  • stress sensitivity

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

Research Article: New Research

  • Independent encoding of orientation and mean luminance by mouse visual cortex
  • Neck Vascular Biomechanical Dysfunction Precedes Brain Biochemical Alterations in a Murine Model of Alzheimer’s Disease
  • Alpha-2 Adrenergic Agonists Reduce Heavy Alcohol Drinking and Improve Cognitive Performance in Mice
Show more Research Article: New Research

Cognition and Behavior

  • Neck Vascular Biomechanical Dysfunction Precedes Brain Biochemical Alterations in a Murine Model of Alzheimer’s Disease
  • Spontaneous oscillatory activity in episodic timing: an EEG replication study and its limitations
  • Neural signatures of engagement and event segmentation during story listening in background noise
Show more Cognition and Behavior

Subjects

  • Cognition and Behavior
  • Home
  • Alerts
  • Follow SFN on BlueSky
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Latest Articles
  • Issue Archive
  • Blog
  • Browse by Topic

Information

  • For Authors
  • For the Media

About

  • About the Journal
  • Editorial Board
  • Privacy Notice
  • Contact
  • Feedback
(eNeuro logo)
(SfN logo)

Copyright © 2026 by the Society for Neuroscience.
eNeuro eISSN: 2373-2822

The ideas and opinions expressed in eNeuro do not necessarily reflect those of SfN or the eNeuro Editorial Board. Publication of an advertisement or other product mention in eNeuro should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in eNeuro.