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Research ArticleResearch Article: Negative Results, Disorders of the Nervous System

Axonal Transport of Lysosomes Is Unaffected in Glucocerebrosidase-Inhibited iPSC-Derived Forebrain Neurons

A. J. Keefe, D. R. Gabrych, Y. Zhu, D. J. Vocadlo and M. A. Silverman
eNeuro 10 October 2023, 10 (10) ENEURO.0079-23.2023; https://doi.org/10.1523/ENEURO.0079-23.2023
A. J. Keefe
1Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada
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D. R. Gabrych
1Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada
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Y. Zhu
3Department of Chemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada
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D. J. Vocadlo
2Centre for Cell Biology, Development, and Disease, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada
3Department of Chemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada
4Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada
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M. A. Silverman
1Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada
2Centre for Cell Biology, Development, and Disease, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada
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eneuro: 10 (10)
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Vol. 10, Issue 10
October 2023
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Axonal Transport of Lysosomes Is Unaffected in Glucocerebrosidase-Inhibited iPSC-Derived Forebrain Neurons
A. J. Keefe, D. R. Gabrych, Y. Zhu, D. J. Vocadlo, M. A. Silverman
eNeuro 10 October 2023, 10 (10) ENEURO.0079-23.2023; DOI: 10.1523/ENEURO.0079-23.2023

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Axonal Transport of Lysosomes Is Unaffected in Glucocerebrosidase-Inhibited iPSC-Derived Forebrain Neurons
A. J. Keefe, D. R. Gabrych, Y. Zhu, D. J. Vocadlo, M. A. Silverman
eNeuro 10 October 2023, 10 (10) ENEURO.0079-23.2023; DOI: 10.1523/ENEURO.0079-23.2023
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Keywords

  • axonal transport
  • conduritol B epoxide
  • glucocerebrosidase
  • lysosomes

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