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Research ArticleResearch Article: Confirmation, Sensory and Motor Systems

Neural Dynamics during Binocular Rivalry: Indications from Human Lateral Geniculate Nucleus

Irem Yildirim and Keith A. Schneider
eNeuro 6 January 2023, 10 (1) ENEURO.0470-22.2022; DOI: https://doi.org/10.1523/ENEURO.0470-22.2022
Irem Yildirim
1Department of Psychological and Brain Sciences, University of Delaware, Newark, Delaware 19716
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Keith A. Schneider
1Department of Psychological and Brain Sciences, University of Delaware, Newark, Delaware 19716
2Center for Biomedical and Brain Imaging, University of Delaware, Newark, Delaware 19716
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    Figure 1.

    The structure of lateral geniculate nucleus. a, the magnocellular-parvocellular structure; b, the eye-specific structure. C, Contralateral eye; I, ipsilateral eye; M, magnocellular; P, parvocellular. Tracings were generated based on the study by Andrews et al. (1997).

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    Figure 2.

    The stimulus presentation for the experimental conditions. Rivalry was the conventional binocular rivalry paradigm in which each eye was presented with a different stimulus, and rotations were counterbalanced across the eyes in the actual experiment. Replay was the physical alternations of the stimuli matching with the perceptual reports of the observer during a previous rivalry block. IOS Rivalry was the interocular switch paradigm in which the rivalry stimuli swapped between the eyes in every few seconds, randomly chosen between 2.5 and 3.5 s.

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    Figure 3.

    Histograms for durations of exclusive perceptions during rivalry. Riv, Rivalry; CW, clockwise rotation; –CW, counterclockwise rotation. In the third column are the histograms collapsed across the two rotations for exclusive perceptions. Black lines reflect the median duration. Bin interval is 1 s.

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    Figure 4.

    GLM results for rivalry and replay in the M and P regions of LGNs. a, Coronal slices of each LGN showing the z scores for the rivalry−replay contrast. The red line delimits the boundary between the M and P regions according to their T1 relaxation time (Yildirim et al., 2022). *p < 0.05, uncorrected for multiple comparisons for voxels. b, Scatterplots of the M and P voxels, indicated by their T1 relaxation time in seconds on the x-axis, showing similar suppression for rivalry and replay. The suppression index on the y-axis was calculated by the B weights. For illustration purposes, the voxels with indices beyond 10 and −10 were plotted at 10 and −10, respectively. Black lines indicate the mean suppression indices for the M and P voxels. Error bars are the SEM. **p = 0.02, Bonferroni corrected for six LGNs.

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    Figure 5.

    fMRI activity around the exclusive eye perceptions during rivalry and replay. The x-axis shows the time around when the stable perception started (time 0), indicated by the participant’s perceptual reports. The y-axis shows the difference in the percentage fMRI signal for the CL eye perceptions versus IL eye perceptions. Error shades are 95% CIs. *p < 0.05.

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eneuro: 10 (1)
eNeuro
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January 2023
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Neural Dynamics during Binocular Rivalry: Indications from Human Lateral Geniculate Nucleus
Irem Yildirim, Keith A. Schneider
eNeuro 6 January 2023, 10 (1) ENEURO.0470-22.2022; DOI: 10.1523/ENEURO.0470-22.2022

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Neural Dynamics during Binocular Rivalry: Indications from Human Lateral Geniculate Nucleus
Irem Yildirim, Keith A. Schneider
eNeuro 6 January 2023, 10 (1) ENEURO.0470-22.2022; DOI: 10.1523/ENEURO.0470-22.2022
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Keywords

  • binocular rivalry
  • fMRI
  • lateral geniculate nucleus
  • magnocellular
  • parvocellular

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