User profiles for V. V. Vyazovskiy

Vladyslav Vyazovskiy

Professor of Sleep Physiology, University of Oxford
Verified email at dpag.ox.ac.uk
Cited by 10209

Sleep and the single neuron: the role of global slow oscillations in individual cell rest

VV Vyazovskiy, KD Harris - Nature Reviews Neuroscience, 2013 - nature.com
Sleep is universal in animals, but its specific functions remain elusive. We propose that
sleep's primary function is to allow individual neurons to perform prophylactic cellular …

Sleep, recovery, and metaregulation: explaining the benefits of sleep

VV Vyazovskiy - Nature and science of sleep, 2015 - Taylor & Francis
A commonly held view is that extended wakefulness is causal for a broad spectrum of
deleterious effects at molecular, cellular, network, physiological, psychological, and behavioral …

Electrophysiological correlates of sleep homeostasis in freely behaving rats

VV Vyazovskiy, C Cirelli, G Tononi - Progress in brain research, 2011 - Elsevier
The electrical activity of the brain does not only reflect the current level of arousal, ongoing
behavior, or involvement in a specific task but is also influenced by what kind of activity, and …

Local sleep in awake rats

VV Vyazovskiy, U Olcese, EC Hanlon, Y Nir, C Cirelli… - Nature, 2011 - nature.com
In an awake state, neurons in the cerebral cortex fire irregularly and electroencephalogram (EEG)
recordings display low-amplitude, high-frequency fluctuations. During sleep, neurons …

[HTML][HTML] Light and cognition: roles for circadian rhythms, sleep, and arousal

AS Fisk, SKE Tam, LA Brown, VV Vyazovskiy… - Frontiers in …, 2018 - frontiersin.org
Light exerts a wide range of effects on mammalian physiology and behavior. As well as
synchronizing circadian rhythms to the external environment, light has been shown to modulate …

Molecular and electrophysiological evidence for net synaptic potentiation in wake and depression in sleep

VV Vyazovskiy, C Cirelli, M Pfister-Genskow… - Nature …, 2008 - nature.com
Plastic changes occurring during wakefulness aid in the acquisition and consolidation of
memories. For some memories, further consolidation requires sleep, but whether plastic …

[PDF][PDF] Regional slow waves and spindles in human sleep

Y Nir, RJ Staba, T Andrillon, VV Vyazovskiy, C Cirelli… - Neuron, 2011 - cell.com
The most prominent EEG events in sleep are slow waves, reflecting a slow (<1 Hz) oscillation
between up and down states in cortical neurons. It is unknown whether slow oscillations …

[PDF][PDF] Cortical firing and sleep homeostasis

VV Vyazovskiy, U Olcese, YM Lazimy, U Faraguna… - Neuron, 2009 - cell.com
The need to sleep grows with the duration of wakefulness and dissipates with time spent
asleep, a process called sleep homeostasis. What are the consequences of staying awake on …

Sleep homeostasis and cortical synchronization: III. A high-density EEG study of sleep slow waves in humans

BA Riedner, VV Vyazovskiy, R Huber, M Massimini… - Sleep, 2007 - academic.oup.com
Study Objectives: The mechanisms responsible for the homeostatic decrease of slow-wave
activity (SWA, defined in this study as electroencephalogram [EEG] power between 0.5 and …

A causal role for brain-derived neurotrophic factor in the homeostatic regulation of sleep

U Faraguna, VV Vyazovskiy, AB Nelson… - Journal of …, 2008 - Soc Neuroscience
Slow-wave activity (SWA), the EEG power between 0.5 and 4 Hz during non-rapid eye
movement (NREM) sleep, is one of the best characterized markers of sleep need, because it …