User profiles for M. Perez-Pouchoulen

Miguel Perez Pouchoulen

School of Medicine University of Maryland
Verified email at som.umaryland.edu
Cited by 494

Foxp2 mediates sex differences in ultrasonic vocalization by rat pups and directs order of maternal retrieval

JM Bowers, M Perez-Pouchoulen… - Journal of …, 2013 - Soc Neuroscience
The FOXP2 gene is central to acquisition of speech and language in humans and vocal
production in birds and mammals. Rodents communicate via ultrasonic vocalizations (USVs) …

Morphological and phagocytic profile of microglia in the developing rat cerebellum

M Perez-Pouchoulen, JW VanRyzin, MM McCarthy - eneuro, 2015 - eneuro.org
Microglia are being increasingly recognized as playing important roles in neurodevelopment.
The cerebellum matures postnatally, undergoing major growth, but the role of microglia in …

Temporary depletion of microglia during the early postnatal period induces lasting sex-dependent and sex-independent effects on behavior in rats

JW VanRyzin, JY Stacey, M Perez-Pouchoulen… - Eneuro, 2016 - eneuro.org
Microglia are the primary immune cells of the brain and function in multiple ways to facilitate
proper brain development. However, our current understanding of how these cells influence …

Androgen modulation of Foxp1 and Foxp2 in the developing rat brain: impact on sex specific vocalization

JM Bowers, M Perez-Pouchoulen, CR Roby… - …, 2014 - academic.oup.com
Sex differences in vocal communication are prevalent in both the animals and humans. The
mechanism(s) mediating gender differences in human language are unknown, although, …

Prenatal exposure to sodium valproate alters androgen receptor expression in the developing cerebellum in a region and age specific manner in male and female rats

M Perez-Pouchoulen, M Miquel, P Saft, B Brug… - International Journal of …, 2016 - Elsevier
Valproic acid (VPA) is an anti-epileptic drug with teratogenicity activity that has been related
to autism. In rodents, exposure to VPA in utero leads to brain abnormalities similar than …

Androgen receptors in Purkinje neurons are modulated by systemic testosterone and sexual training in a region-specific manner in the male rat

M Perez-Pouchoulen, R Toledo, LI Garcia… - Physiology & …, 2016 - Elsevier
The androgen receptor (AR) is a widely distributed molecule indicating the spread actions
of its ligand steroid, and plays an important role underlying male sexual behavior. …

Generation of an Iba1-EGFP transgenic rat for the study of microglia in an outbred rodent strain

…, KE Kight, AE Marquardt, M Perez-Pouchoulen… - Eneuro, 2021 - eneuro.org
Neuroscience has been transformed by the ability to genetically modify inbred mice, including
the ability to express fluorescent markers specific to cell types or activation states. This …

Regulatory control of microglial phagocytosis by estradiol and prostaglandin E2 in the developing rat cerebellum

M Perez-Pouchoulen, SJ Yu, CR Roby, N Bonsavage… - The Cerebellum, 2019 - Springer
Microglia are essential to sculpting the developing brain, and they achieve this in part through
the process of phagocytosis which is regulated by microenvironmental signals associated …

The cerebellum in Austim

M Perez-Pouchoulen, M Miquel, P Saft, B Brug… - 2012 - repositori.uji.es
Autism is considered as a neurodevelopmental disorder which affects boys more than girls,
in a proportion 4:1 respectively. Autism presents neuroanatomical abnormalities located in …

Fatty acid amide hydrolase inhibition and N‐arachidonoylethanolamine modulation by isoflavonoids: A novel target for upcoming antidepressants

…, JW VanRyzin, M PerezPouchoulen… - Pharmacology …, 2022 - Wiley Online Library
Modulation of the endocannabinoid system (ECS) is a novel putative target for therapeutic
intervention in depressive disorders. Altering concentrations of one of the principal …