Modulators of 14-3-3 protein–protein interactions
…, A Karawajczyk, J Eickhoff, J Davis… - Journal of medicinal …, 2017 - ACS Publications
Direct interactions between proteins are essential for the regulation of their functions in
biological pathways. Targeting the complex network of protein–protein interactions (PPIs) has …
biological pathways. Targeting the complex network of protein–protein interactions (PPIs) has …
Stabilization of protein-protein interactions in drug discovery
…, MWD Perry, A Karawajczyk, J Eickhoff… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: PPIs are involved in every disease and specific modulation of these PPIs with
small molecules would significantly improve our prospects of developing therapeutic agents. …
small molecules would significantly improve our prospects of developing therapeutic agents. …
Performance of low-risk criteria in the evaluation of young infants with fever: review of the literature
AR Huppler, JC Eickhoff, ER Wald - Pediatrics, 2010 - publications.aap.org
OBJECTIVE: The goal was to determine the performance of low-risk criteria for serious
bacterial illnesses (SBIs) in febrile infants in prospective studies in which empiric antibiotic …
bacterial illnesses (SBIs) in febrile infants in prospective studies in which empiric antibiotic …
In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia
…, A Gendron-Fitzpatrick, J Eickhoff… - Proceedings of the …, 2007 - National Acad Sciences
Metabolic imaging of the relative amounts of reduced NADH and FAD and the microenvironment
of these metabolic electron carriers can be used to noninvasively monitor changes in …
of these metabolic electron carriers can be used to noninvasively monitor changes in …
[HTML][HTML] Aligned collagen is a prognostic signature for survival in human breast carcinoma
MW Conklin, JC Eickhoff, KM Riching… - The American journal of …, 2011 - Elsevier
Evidence for the potent influence of stromal organization and function on invasion and
metastasis of breast tumors is ever growing. We have performed a rigorous examination of the …
metastasis of breast tumors is ever growing. We have performed a rigorous examination of the …
A market basket survey of inorganic arsenic in food
RA Schoof, LJ Yost, J Eickhoff, EA Crecelius… - Food and Chemical …, 1999 - Elsevier
Dietary arsenic intake estimates based on surveys of total arsenic concentrations appear to
be dominated by intake of the relatively non-toxic, organic arsenic forms found in seafood. …
be dominated by intake of the relatively non-toxic, organic arsenic forms found in seafood. …
“Facebook depression?” Social networking site use and depression in older adolescents
LA Jelenchick, JC Eickhoff, MA Moreno - Journal of Adolescent Health, 2013 - Elsevier
PURPOSE: To evaluate the association between social networking site (SNS) use and
depression in older adolescents using an experience sample method (ESM) approach. …
depression in older adolescents using an experience sample method (ESM) approach. …
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells
Tumour metastasis is the primary cause of mortality in cancer patients and remains the key
challenge for cancer therapy 1 . New therapeutic approaches to block inhibitory pathways of …
challenge for cancer therapy 1 . New therapeutic approaches to block inhibitory pathways of …
Gasdermin D plays a vital role in the generation of neutrophil extracellular traps
…, R Di Lucrezia, S Kordes, S Menninger, J Eickhoff… - Science …, 2018 - science.org
The death of a cell is an inevitable part of its biology. During homeostasis, most cells die
through apoptosis. If homeostasis is disturbed, cell death can switch to proinflammatory forms of …
through apoptosis. If homeostasis is disturbed, cell death can switch to proinflammatory forms of …
In vivo multiphoton fluorescence lifetime imaging<?xpp qa?> of protein-bound and free nicotinamide adenine dinucleotide in normal and precancerous epithelia
…, A Gendron-Fitzpatrick, J Eickhoff… - … of biomedical optics, 2007 - spiedigitallibrary.org
Multiphoton fluorescence lifetime imaging microscopy (FLIM) is a noninvasive, cellular
resolution, 3-D functional imaging technique. We investigate the potential for in vivo precancer …
resolution, 3-D functional imaging technique. We investigate the potential for in vivo precancer …