User profiles for J. Casanova

Jean-Laurent Casanova, MD, PhD

- Verified email at rockefeller.edu - Cited by 121256

Jose Casanova

- Verified email at georgetown.edu - Cited by 22162

[BOOK][B] Public religions in the modern world

J Casanova - 2011 - books.google.com
In a sweeping reconsideration of the relation between religion and modernity, Jose Casanova
Casanova looks at five cases from two religious traditions (Catholicism and Protestantism) …

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

…, ZY Liu, K Nafa, L Borsu, J Sadowska, J Casanova… - Nature medicine, 2017 - nature.com
Tumor molecular profiling is a fundamental component of precision oncology, enabling the
identification of genomic alterations in genes and pathways that can be targeted …

[HTML][HTML] Guidelines and definitions for research on epithelial–mesenchymal transition

…, M Bronner, K Campbell, A Cano, J Casanova… - … reviews Molecular cell …, 2020 - nature.com
Epithelial–mesenchymal transition (EMT) encompasses dynamic changes in cellular organization
from epithelial to mesenchymal phenotypes, which leads to functional changes in cell …

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

…, LD Notarangelo, L Abel, HC Su, JL Casanova - Science, 2020 - science.org
INTRODUCTION Interindividual clinical variability is vast in humans infected with severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ranging from silent infection to rapid …

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

…, P Nusbaum, F Selz, C Hue, S Certain, JL Casanova… - Science, 2000 - science.org
Severe combined immunodeficiency–X1 (SCID-X1) is an X-linked inherited disorder
characterized by an early block in T and natural killer (NK) lymphocyte differentiation. This block is …

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

…, LD Notarangelo, A Cobat, HC Su, JL Casanova - Science, 2020 - science.org
INTRODUCTION Clinical outcomes of human severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) infection range from silent infection to lethal coronavirus disease 2019 (…

[HTML][HTML] Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): a hybridization capture-based next-generation …

…, C O'Reilly, J Sadowska, J Casanova… - The Journal of molecular …, 2015 - Elsevier
The identification of specific genetic alterations as key oncogenic drivers and the development
of targeted therapies are together transforming clinical oncology and creating a pressing …

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

…, F Ramsdell, J Peake, F Faravelli, JL Casanova… - Nature …, 2001 - nature.com
To determine whether human X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy
syndrome (IPEX; MIM 304930) is the genetic equivalent of the scurfy (sf) mouse, we …

[PDF][PDF] Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors

…, D Moshous, C Picard, JP Jais, D D'Cruz, JL Casanova… - Immunity, 2010 - cell.com
Monocytes are effectors of the inflammatory response to microbes. Human CD14 +
monocytes specialize in phagocytosis and production of reactive oxygen species and secrete …

Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic in Paris, France: prospective observational study

…, S Biscardi, P Frange, M Chalumeau, JL Casanova… - bmj, 2020 - bmj.com
Objectives To describe the characteristics of children and adolescents affected by an outbreak
of Kawasaki-like multisystem inflammatory syndrome and to evaluate a potential temporal …