Shaping of signal transmission at the photoreceptor synapse by EAAT2 glutamate transporters

S Niklaus, L Cadetti, CM vom Berg-Maurer, A Lehnherr… - eneuro, 2017 - eneuro.org
Photoreceptor ribbon synapses tonically release glutamate. To ensure efficient signal
transmission and prevent glutamate toxicity, a highly efficient glutamate removal system provided …

Proper migration and axon outgrowth of zebrafish cranial motoneuron subpopulations require the cell adhesion molecule MDGA2A

…, CJ Burckhardt, A Lehnherr… - Biology …, 2015 - journals.biologists.com
The formation of functional neuronal circuits relies on accurate migration and proper axonal
outgrowth of neuronal precursors. On the route to their targets migrating cells and growing …

Photons or electrons? A critical comparison of electrochemistry and photoredox catalysis for organic synthesis

NES Tay, D Lehnherr, T Rovis - Chemical reviews, 2021 - ACS Publications
Redox processes are at the heart of synthetic methods that rely on either electrochemistry or
photoredox catalysis, but how do electrochemistry and photoredox catalysis compare? Both …

Methylmercury biogeochemistry: a review with special reference to Arctic aquatic ecosystems

I Lehnherr - Environmental Reviews, 2014 - cdnsciencepub.com
There has been increasing concern about mercury (Hg) levels in marine and freshwater
organisms in the Arctic, due to the importance of traditional country foods such as fish and …

[HTML][HTML] Atmospheric mercury in the Canadian Arctic. Part I: A review of recent field measurements

A Steffen, I Lehnherr, A Cole, P Ariya, A Dastoor… - Science of the Total …, 2015 - Elsevier
Long-range atmospheric transport and deposition are important sources of mercury (Hg) to
Arctic aquatic and terrestrial ecosystems. We review here recent progress made in the study …

Addiction protein Phd of plasmid prophage P1 is a substrate of the ClpXP serine protease of Escherichia coli.

H Lehnherr, MB Yarmolinsky - Proceedings of the National …, 1995 - National Acad Sciences
Plasmid-encoded addiction genes augment the apparent stability of various low copy number
bacterial plasmids by selectively killing plasmid-free (cured) segregants or their progeny. …

Unlocking the potential of high-throughput experimentation for electrochemistry with a standardized microscale reactor

…, NA Strotman, D Kalyani, D Lehnherr… - ACS Central …, 2021 - ACS Publications
Organic electrochemistry has emerged as an enabling and sustainable technology in modern
organic synthesis. Despite the recent renaissance of electrosynthesis, the broad adoption …

Kilo-Scale Electrochemical Oxidation of a Thioether to a Sulfone: A Workflow for Scaling up Electrosynthesis

C Bottecchia, D Lehnherr, F Lévesque… - … Process Research & …, 2022 - ACS Publications
Organic electrosynthesis is a rapidly evolving field, providing powerful methods to assemble
targets of interest in organic synthesis. Concerns around the scalability of electrochemical …

A mass budget for mercury and methylmercury in the Arctic Ocean

…, AT Schartup, JA Fisher, I Lehnherr… - Global …, 2016 - Wiley Online Library
Elevated biological concentrations of methylmercury (MeHg), a bioaccumulative neurotoxin,
are observed throughout the Arctic Ocean, but major sources and degradation pathways in …

Manufacturing process development for belzutifan, part 2: a continuous flow visible-light-induced benzylic bromination

…, L Tan, G Spencer, J Nappi, D Lehnherr… - … Process Research & …, 2021 - ACS Publications
We report the development and scale-up of a continuous flow photochemical benzylic
bromination en route to belzutifan (MK-6482), a small molecule for the treatment of renal cell …