The activation of cAMP-response element binding protein (CREB)-dependent gene expression
seems a crucial step in the molecular cascade that mediates the formation of long-lasting …

Cellular and molecular studies of both implicit and explicit memory suggest that experience‐dependent
modulation of synaptic strength and structure is a fundamental mechanism by …

The treatment of memory disorders, such as the gradual weakening of memory with age, the
ravages of Alzheimer’s disease and the cognitive deficits in various forms of mental …

Restricted and regulated expression in mice of VP16-CREB, a constitutively active form of
CREB, in hippocampal CA1 neurons lowers the threshold for eliciting a persistent late phase …

Inhibitors in myelin play a major role in preventing spontaneous axonal regeneration after
CNS injury. Elevation of cAMP overcomes this inhibition, in a transcription-dependent manner, …

Expression of VP16-CREB, a constitutively active form of CREB, in hippocampal neurons of
the CA1 region lowers the threshold for eliciting the late, persistent phase of long-term …

Remodeling chromatin is essential for cAMP-regulated gene expression, necessary not only
for development but also for memory storage and other enduring mental states. Histone …

Dendritic spines are small protrusions from dendritic shafts that contain the postsynaptic
sites of glutamatergic synapses in the brain. Spines undergo dramatic activity-dependent …

We studied a mouse model of the haploinsufficiency form of Rubinstein-Taybi syndrome (RTS),
an inheritable disorder caused by mutations in the gene encoding the CREB binding …

Lednieer’s stimulating revtewlin 1972. introducing the concept of heterocycles as latent
functionalities. and the publication of the popular book. Heteroeyeles in Orgaitie Synthesis. 2 by …