[HTML][HTML] Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors

H Nakatomi, T Kuriu, S Okabe, S Yamamoto, O Hatano… - Cell, 2002 - cell.com
The adult brain is extremely vulnerable to various insults. The recent discovery of neural
progenitors in adult mammals, however, raises the possibility of repairing damaged tissue by …

Continual remodeling of postsynaptic density and its regulation by synaptic activity

S Okabe, HD Kim, A Miwa, T Kuriu, H Okado - Nature neuroscience, 1999 - nature.com
… control (paired t-test; p < 0.05) and APV treated cells (paired t-test; p < 0.01). All pharmacological
treatments significantly inhibited the rates of both appearance and disappearance (t-test…

Differential control of postsynaptic density scaffolds via actin-dependent and-independent mechanisms

T Kuriu, A Inoue, H Bito, K Sobue… - Journal of …, 2006 - Soc Neuroscience
… The difference of EGFP concentration between the dendritic shaft (C 0 ) and the spine [C(t)]
is proportional to the movement of EGFP molecules through the spine neck. This relationship …

[HTML][HTML] Enhanced synapse remodelling as a common phenotype in mouse models of autism

…, S Tanaka, T Kuriu, K Tabuchi, T Takumi… - Nature …, 2014 - nature.com
Developmental deficits in neuronal connectivity are considered to be present in patients with
autism spectrum disorders (ASDs). Here we examine this possibility by using in vivo spine …

[HTML][HTML] Doublecortin-like kinase enhances dendritic remodelling and negatively regulates synapse maturation

…, Y Kashiwagi, T Kuriu, H Iwasaki, T Tanaka… - Nature …, 2013 - nature.com
Dendritic morphogenesis and formation of synapses at appropriate dendritic locations are
essential for the establishment of proper neuronal connectivity. Recent imaging studies …

Regulation of dendritic spine morphology by an NMDA receptor‐associated Rho GTPase‐activating protein, p250GAP

T Nakazawa, T Kuriu, T Tezuka… - Journal of …, 2008 - Wiley Online Library
The NMDA receptor regulates spine morphological plasticity by modulating Rho GTPases.
However, the molecular mechanisms for NMDA receptor‐mediated regulation of Rho …

[HTML][HTML] Multiple alterations in glutamatergic transmission and dopamine D2 receptor splicing in induced pluripotent stem cell-derived neurons from patients with …

K Yamamoto, T Kuriu, K Matsumura… - Translational …, 2021 - nature.com
… We applied Student’s t-test for statistical analyses for the biochemical data under the
assumptions of normality and equality of variance (Supplementary Table 1). Accordingly, the …

[HTML][HTML] Developmental stage-dependent regulation of spine formation by calcium-calmodulin-dependent protein kinase IIα and Rap1

S Cornelia Koeberle, S Tanaka, T Kuriu, H Iwasaki… - Scientific Reports, 2017 - nature.com
The roles of calcium-calmodulin-dependent protein kinase II-alpha (CaMKIIα) in the expression
of long-term synaptic plasticity in the adult brain have been extensively studied. However…

Action Spectra for Step‐Up Photophobic Response in Blepharisma

…, S MATSUOKA, Y YAMAOKA, T KURIU… - The Journal of …, 1992 - Wiley Online Library
The cells of Blepharisma which possess red pigment (blepharismin) show step‐up photophobic
response (temporal ciliary reversal induced by a sudden increase in light intensity). …

Necl2/3-mediated mechanism for tripartite synapse formation

…, T Kameyama, R Komaki, T Shimizu, T Kuriu… - …, 2023 - journals.biologists.com
Ramified, polarized protoplasmic astrocytes interact with synapses via perisynaptic
astrocyte processes (PAPs) to form tripartite synapses. These astrocyte-synapse interactions …