[HTML][HTML] Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors
H Nakatomi, T Kuriu, S Okabe, S Yamamoto, O Hatano… - Cell, 2002 - cell.com
The adult brain is extremely vulnerable to various insults. The recent discovery of neural
progenitors in adult mammals, however, raises the possibility of repairing damaged tissue by …
progenitors in adult mammals, however, raises the possibility of repairing damaged tissue by …
Continual remodeling of postsynaptic density and its regulation by synaptic activity
S Okabe, HD Kim, A Miwa, T Kuriu, H Okado - Nature neuroscience, 1999 - nature.com
… control (paired t-test; p < 0.05) and APV treated cells (paired t-test; p < 0.01). All pharmacological
treatments significantly inhibited the rates of both appearance and disappearance (t-test…
treatments significantly inhibited the rates of both appearance and disappearance (t-test…
Differential control of postsynaptic density scaffolds via actin-dependent and-independent mechanisms
T Kuriu, A Inoue, H Bito, K Sobue… - Journal of …, 2006 - Soc Neuroscience
… The difference of EGFP concentration between the dendritic shaft (C 0 ) and the spine [C(t)]
is proportional to the movement of EGFP molecules through the spine neck. This relationship …
is proportional to the movement of EGFP molecules through the spine neck. This relationship …
[HTML][HTML] Enhanced synapse remodelling as a common phenotype in mouse models of autism
Developmental deficits in neuronal connectivity are considered to be present in patients with
autism spectrum disorders (ASDs). Here we examine this possibility by using in vivo spine …
autism spectrum disorders (ASDs). Here we examine this possibility by using in vivo spine …
[HTML][HTML] Doublecortin-like kinase enhances dendritic remodelling and negatively regulates synapse maturation
Dendritic morphogenesis and formation of synapses at appropriate dendritic locations are
essential for the establishment of proper neuronal connectivity. Recent imaging studies …
essential for the establishment of proper neuronal connectivity. Recent imaging studies …
Regulation of dendritic spine morphology by an NMDA receptor‐associated Rho GTPase‐activating protein, p250GAP
T Nakazawa, T Kuriu, T Tezuka… - Journal of …, 2008 - Wiley Online Library
The NMDA receptor regulates spine morphological plasticity by modulating Rho GTPases.
However, the molecular mechanisms for NMDA receptor‐mediated regulation of Rho …
However, the molecular mechanisms for NMDA receptor‐mediated regulation of Rho …
[HTML][HTML] Multiple alterations in glutamatergic transmission and dopamine D2 receptor splicing in induced pluripotent stem cell-derived neurons from patients with …
K Yamamoto, T Kuriu, K Matsumura… - Translational …, 2021 - nature.com
… We applied Student’s t-test for statistical analyses for the biochemical data under the
assumptions of normality and equality of variance (Supplementary Table 1). Accordingly, the …
assumptions of normality and equality of variance (Supplementary Table 1). Accordingly, the …
[HTML][HTML] Developmental stage-dependent regulation of spine formation by calcium-calmodulin-dependent protein kinase IIα and Rap1
S Cornelia Koeberle, S Tanaka, T Kuriu, H Iwasaki… - Scientific Reports, 2017 - nature.com
The roles of calcium-calmodulin-dependent protein kinase II-alpha (CaMKIIα) in the expression
of long-term synaptic plasticity in the adult brain have been extensively studied. However…
of long-term synaptic plasticity in the adult brain have been extensively studied. However…
Action Spectra for Step‐Up Photophobic Response in Blepharisma
…, S MATSUOKA, Y YAMAOKA, T KURIU… - The Journal of …, 1992 - Wiley Online Library
The cells of Blepharisma which possess red pigment (blepharismin) show step‐up photophobic
response (temporal ciliary reversal induced by a sudden increase in light intensity). …
response (temporal ciliary reversal induced by a sudden increase in light intensity). …
Necl2/3-mediated mechanism for tripartite synapse formation
…, T Kameyama, R Komaki, T Shimizu, T Kuriu… - …, 2023 - journals.biologists.com
Ramified, polarized protoplasmic astrocytes interact with synapses via perisynaptic
astrocyte processes (PAPs) to form tripartite synapses. These astrocyte-synapse interactions …
astrocyte processes (PAPs) to form tripartite synapses. These astrocyte-synapse interactions …