Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegans

S Honjoh, T Yamamoto, M Uno, E Nishida - Nature, 2009 - nature.com
Dietary restriction is the most effective and reproducible intervention to extend lifespan in
divergent species 1 . In mammals, two regimens of dietary restriction, intermittent fasting (IF) …

[PDF][PDF] ERK activation propagates in epithelial cell sheets and regulates their migration during wound healing

Y Matsubayashi, M Ebisuya, S Honjoh, E Nishida - Current Biology, 2004 - cell.com
In epithelial cell movements, which occur during wound healing or embryonic morphogenesis,
sheets of cells move together as a unit [1, 2]. Molecular mechanisms that regulate this …

[PDF][PDF] Local slow waves in superficial layers of primary cortical areas during REM sleep

CM Funk, S Honjoh, AV Rodriguez, C Cirelli, G Tononi - Current Biology, 2016 - cell.com
… Sleep was scored in 4-s epochs according to established criteria, and we considered all
consolidated sleep episodes throughout the entire light phase, when mice sleep most of the …

[HTML][HTML] The ERK-MAPK pathway regulates longevity through SKN-1 and insulin-like signaling in Caenorhabditis elegans

…, H Inoue, S Ookuma, T Satoh, K Kano, S Honjoh… - Journal of Biological …, 2010 - ASBMB
It has not been determined yet whether the ERK-MAPK pathway regulates longevity of
metazoans. Here, we show that the Caenorhabditis elegans ERK cascade promotes longevity …

[HTML][HTML] Regulation of cortical activity and arousal by the matrix cells of the ventromedial thalamic nucleus

S Honjoh, S Sasai, SS Schiereck, H Nagai… - Nature …, 2018 - nature.com
The “non-specific” ventromedial thalamic nucleus (VM) has long been considered a candidate
for mediating cortical arousal due to its diffuse, superficial projections, but direct evidence …

A new, mechanistic model for organic carbon fluxes in the ocean based on the quantitative association of POC with ballast minerals

RA Armstrong, C Lee, JI Hedges, S Honjo… - Deep Sea Research …, 2001 - Elsevier
… -ENSO conditions); values from 1S and 3S were omitted because they were sampled in only
… Whatever the mechanism(s), we find that there is a strong quantitative association between …

The distribution of oceanic coccolithophorids in the Pacific

H Okada, S Honjo - Deep Sea Research and Oceanographic Abstracts, 1973 - Elsevier
… it was transitional along traverse 5 between 5S and 10S (Fig. 4). Zones D and E then seem
to correspond to the South Equatorial Current and the weak South Equatorial Countercurrent. …

[PDF][PDF] A fasting-responsive signaling pathway that extends life span in C. elegans

…, S Honjoh, M Matsuda, H Hoshikawa, S Kishimoto… - Cell reports, 2013 - cell.com
Intermittent fasting is one of the most effective dietary restriction regimens that extend life span
in C. elegans and mammals. Fasting-stimulus responses are key to the longevity response…

Particulate organic carbon fluxes to the ocean interior and factors controlling the biological pump: A synthesis of global sediment trap programs since 1983

S Honjo, SJ Manganini, RA Krishfield… - Progress in …, 2008 - Elsevier
… CO 2 (∑CO 2 ) sinks in the world ocean’s interior and at the seafloor. Depending upon depth,
… regulating Earth’s climate by preventing runaway accumulation of CO 2 in the atmosphere. …

Factors controlling the flux of organic carbon to the bathypelagic zone of the ocean

…, S Honjo, R Krishfield, S Manganini - Global …, 2002 - Wiley Online Library
… were obtained at ∼1000 m depth [Honjo et al., 2000]. They were not included in this study,
but for one sediment trap deployed at 4224 m (AESOPS-2; 56.90S, 170.2W), where relatively …