Nanoparticle-assisted combination therapies for effective cancer treatment
Combination chemotherapy and nanoparticle drug delivery are two areas that have shown
significant promise in cancer treatment. Combined therapy of two or more drugs promotes …
significant promise in cancer treatment. Combined therapy of two or more drugs promotes …
[HTML][HTML] Microplastics in environment: global concern, challenges, and controlling measures
Plastic pollution in various forms has emerged as the most severe environmental threat.
Small plastic chunks, such as microplastics and nanoplastics derived from primary and …
Small plastic chunks, such as microplastics and nanoplastics derived from primary and …
COPD and gender differences: an update
S Aryal, E Diaz-Guzman, DM Mannino - Translational Research, 2013 - Elsevier
… Nevertheless, women’s increased susceptibility to COPD may start early in childhood; girls
experience a larger reduction in lung function than boys when exposed either to tobacco …
experience a larger reduction in lung function than boys when exposed either to tobacco …
Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform
Efforts to extend nanoparticle residence time in vivo have inspired many strategies in particle
surface modifications to bypass macrophage uptake and systemic clearance. Here we …
surface modifications to bypass macrophage uptake and systemic clearance. Here we …
Moving beyond P values: data analysis with estimation graphics
… Here we describe the estimation graphic, a plot that displays an experimental dataset’s
complete statistical information. We also introduce software that makes high-quality estimation …
complete statistical information. We also introduce software that makes high-quality estimation …
[HTML][HTML] Total phenolic content, flavonoid content and antioxidant potential of wild vegetables from Western Nepal
… Finally, 2.5 mL of the supernatant was mixed with 2.5 mL deionized water and 0.5 mL 0.1%
(w/v) ferric chloride, and Perl’s Prussian blue colour was measured at λ max 700 nm against …
(w/v) ferric chloride, and Perl’s Prussian blue colour was measured at λ max 700 nm against …
Artificial intelligence and machine learning to fight COVID-19
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2)(13), has become an unprecedented public health crisis. …
coronavirus 2 (SARS-CoV-2)(13), has become an unprecedented public health crisis. …
Twenty-three unsolved problems in hydrology (UPH)–a community perspective
This paper is the outcome of a community initiative to identify major unsolved scientific
problems in hydrology motivated by a need for stronger harmonisation of research efforts. The …
problems in hydrology motivated by a need for stronger harmonisation of research efforts. The …
Polymer− cisplatin conjugate nanoparticles for acid-responsive drug delivery
We report the synthesis of novel acid-responsive therapeutic nanoparticles (NPs) with sub-100
nm size consisting of polymer−cisplatin conjugates. The uniqueness of these drug …
nm size consisting of polymer−cisplatin conjugates. The uniqueness of these drug …
Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy
P Maycotte, S Aryal, CT Cummings, J Thorburn… - Autophagy, 2012 - Taylor & Francis
Chloroquine (CQ) is a 4-aminoquinoline drug used for the treatment of diverse diseases. It
inhibits lysosomal acidification and therefore prevents autophagy by blocking …
inhibits lysosomal acidification and therefore prevents autophagy by blocking …