Molecular basis of semaphorin‐mediated axon guidance

F Nakamura, RG Kalb… - Journal of neurobiology, 2000 - Wiley Online Library
The semaphorin family of proteins constitute one of the major cues for axonal guidance. The
prototypic member of this family is Sema3A, previously designated semD/III or collapsin‐1. …

[HTML][HTML] Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors

…, F Nakamura, LH Wang, Y Murakami, RG Kalb… - Cell, 1999 - cell.com
Class 1 and 3 semaphorins repulse axons but bind to different cell surface proteins. We find
that the two known semaphorin-binding proteins, plexin 1 (Plex 1) and neuropilin-1 (NP-1), …

[HTML][HTML] Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway

…, D Fulton, K Mahboubi, RG Kalb… - Journal of Biological …, 2000 - ASBMB
A productive angiogenic response must couple to the survival machinery of endothelial cells
to preserve the integrity of newly formed vessels. Angiopoietin-1 (Ang-1) is an endothelium-…

AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location

…, MD Geschwind, L Bataller, RG Kalb… - Annals of …, 2009 - Wiley Online Library
Objective To report the clinical and immunological features of a novel autoantigen related to
limbic encephalitis (LE) and the effect of patients' antibodies on neuronal cultures. Methods …

A yeast functional screen predicts new candidate ALS disease genes

…, L McCluskey, R Greene, RG Kalb… - Proceedings of the …, 2011 - National Acad Sciences
Amyotrophic lateral sclerosis (ALS) is a devastating and universally fatal neurodegenerative
disease. Mutations in two related RNA-binding proteins, TDP-43 and FUS, that harbor prion-…

Expression of neural proteoglycans correlates with the acquisition of mature neuronal properties in the mammalian brain

S Hockfield, RG Kalb, S Zaremba… - Cold Spring Harbor …, 1990 - symposium.cshlp.org
… the neuromuscular unit required for Cat-301 expression indicate that large-diameter, but
not smalldiameter, primary afferent inputs mediate activitydependent Cat-301 expression (Kalb

[PDF][PDF] Poly (ADP-ribose) prevents pathological phase separation of TDP-43 by promoting liquid demixing and stress granule localization

…, L Guo, J Mojsilovic-Petrovic, V Tran, RG Kalb… - Molecular cell, 2018 - cell.com
In amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD), cytoplasmic
aggregates of hyperphosphorylated TDP-43 accumulate and colocalize with some stress …

[PDF][PDF] Neuropilin-1 extracellular domains mediate semaphorin D/III-induced growth cone collapse

F Nakamura, M Tanaka, T Takahashi, RG Kalb… - Neuron, 1998 - cell.com
Somatosensory axon outgrowth is repulsed when soluble semaphorin D (semD) binds to
growth cone neuropilin-1 (Npn-1). Here, semD ligand binding studies of Npn-1 mutants …

Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis

…, R Greene, H Hakonarson, RG Kalb… - Human molecular …, 2012 - academic.oup.com
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting motor
neurons. Mutations in related RNA-binding proteins TDP-43, FUS/TLS and TAF15 have been …

Sensitization to morphine induced by viral-mediated gene transfer

…, VA Boundy, CN Haile, SB Lane, RG Kalb… - Science, 1997 - science.org
Repeated administration of morphine sensitizes animals to the stimulant and rewarding
properties of the drug. It also selectively increases expression of GluR1 (an AMPA glutamate …