… In responders, stronger VNS-induced theta desynchronization (p < 0.05) was found in
sleep but not during wakefulness. There also is some evidence showing that chronic VNS …

The World Health Organization estimates that globally 2.4 million people are diagnosed with
epilepsy each year. In nearly 30% of these cases, epilepsy cannot be properly controlled by …

Gene-regulatory network analysis is a powerful approach to elucidate the molecular
processes and pathways underlying complex disease. Here we employ systems genetics …

… differences were considered significant when adjusted P was <0.1. Comparisons between
… an adjusted p < 0.1 as significant. For plasma, we applied ANOVA analysis and a P cutoff of …

… To analyze the data, one-way ANOVA and post hoc Dunnett's test (p < 0.05 and p < 0.001)
or Mann–Whitney test (statistical significance at p < 0.05) were used, as indicated in the figure …

An increase in the release of excitatory amino acids has consistently been observed in the
hippocampus during seizures, both in humans and animals. However, very little or nothing is …

Lack of translation of data obtained in preclinical trials to clinic has kindled researchers to
develop new methodologies to increase the power and reproducibility of preclinical studies. …

… A 2 fold-change filter (n = 141) and the unpaired t-test were applied (p<0.05; False Discovery
Rate-FDR = 7%). … Differences between groups were considered significant when P < 0.05. …

Neuronal physiology requires activity-driven protein translation, a process in which translation
initiation factors are key players. We focus on eukaryotic initiation factor 4B (eIF4B), a …

… effects meta-analysis of miRNA changes in the three models of epileptogenesis and adopting
a stringent correction for multiple testing to minimize false positives (Bonferroni adjusted p …