The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina

…, LP de Sevilla Müller, NC Brecha - Journal of …, 2014 - Wiley Online Library
There are few neurochemical markers that reliably identify retinal ganglion cells (RGCs), which
are a heterogeneous population of cells that integrate and transmit the visual signal from …

GAT-1, a high-affinity GABA plasma membrane transporter, is localized to neurons and astroglia in the cerebral cortex

A Minelli, NC Brecha, C Karschin… - Journal of …, 1995 - Soc Neuroscience
High affinity, GABA plasma membrane transporters influence the action of GABA, the main
inhibitory neurotransmitter. The cellular expression of GAT-1, a prominent GABA transporter, …

Agonist-selective endocytosis of mu opioid receptor by neurons in vivo.

…, M Von Zastrow, C Evans, NC Brecha - Proceedings of the …, 1996 - National Acad Sciences
Opiate alkaloids are potent analgesics that exert multiple pharmacological effects in the
nervous system by activating G protein-coupled receptors. Receptor internalization upon …

GAT-3, a high-affinity GABA plasma membrane transporter, is localized to astrocytic processes, and it is not confined to the vicinity of GABAergic synapses in the …

A Minelli, S DeBiasi, NC Brecha… - Journal of …, 1996 - Soc Neuroscience
The termination of GABA synaptic action by high-affinity, Na + -dependent, neuronal, and
glial plasma membrane transporters plays an important role in regulating neuronal activity in …

[HTML][HTML] Activation of the Nrf2/HO-1 antioxidant pathway contributes to the protective effects of Lycium barbarum polysaccharides in the rodent retina after ischemia …

M He, H Pan, RCC Chang, KF So, NC Brecha, M Pu - PloS one, 2014 - journals.plos.org
Lycium barbarum polysaccharides (LBP), extracts from the wolfberries, are protective to
retina after ischemia-reperfusion (I/R). The antioxidant response element (ARE)–mediated …

GABA plasma membrane transporters, GAT‐1 and GAT‐3, display different distributions in the rat hippocampus

…, WMY Tong, NC Brecha - Journal of Comparative …, 1996 - Wiley Online Library
This study evaluates the distribution of two high affinity gamma‐aminobutyric acid (GABA)
transporters (GAT‐1 and GAT‐3) in the rat hippocampus using immunocytochemistry and …

The nob2 mouse, a null mutation in Cacna1f: anatomical and functional abnormalities in the outer retina and their consequences on ganglion cell visual responses

…, JR Heckenlively, PR Bayley, NC Brecha… - Visual …, 2006 - cambridge.org
Glutamate release from photoreceptor terminals is controlled by voltage-dependent calcium
channels (VDCCs). In humans, mutations in the Cacna1f gene, encoding the α1F subunit of …

[HTML][HTML] Horizontal cell feedback to cone photoreceptors in mammalian retina: novel insights from the GABA-pH hybrid model

…, CF McHugh, AA Hirano, NC Brecha - Frontiers in Cellular …, 2020 - frontiersin.org
How neurons in the eye feed signals back to photoreceptors to optimize sensitivity to patterns
of light appears to be mediated by one or more unconventional mechanisms. Via these …

Calcitonin gene-related peptide (CGRP) in the rat central nervous system: patterns of immunoreactivity and receptor binding sites

L Kruger, PW Mantyh, C Sternini, NC Brecha… - Brain research, 1988 - Elsevier
… and Brecha, NC, Distribution and characterization of calcitonin gene-related peptide
immunoreactivity in the digestive system of normal and capsaicin-treated rats, Gastroenterology, 93 (…

[PDF][PDF] Elevating growth factor responsiveness and axon regeneration by modulating presynaptic inputs

…, A Jacobi, C Wang, A Goel, AA Hirano, NC Brecha… - Neuron, 2019 - cell.com
Despite robust effects on immature neurons, growth factors minimally promote axon
regeneration in the adult central nervous system (CNS). Attempting to improve growth-factor …