User profiles for M. Murphy

Michael P Murphy

- Verified email at mrc-mbu.cam.ac.uk - Cited by 76295

Michael Murphy

- Verified email at ucc.ie - Cited by 13497

How mitochondria produce reactive oxygen species

MP Murphy - Biochemical journal, 2009 - portlandpress.com
The production of ROS (reactive oxygen species) by mammalian mitochondria is important
because it underlies oxidative damage in many pathologies and contributes to retrograde …

[PDF][PDF] Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease

…, X Jiang, A Linkermann, ME Murphy, M Overholtzer… - Cell, 2017 - cell.com
Ferroptosis is a form of regulated cell death characterized by the iron-dependent accumulation
of lipid hydroperoxides to lethal levels. Emerging evidence suggests that ferroptosis …

Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology

…, GE Mann, MP Murphy, M Yamamoto… - … Reviews Molecular Cell …, 2022 - nature.com
‘Reactive oxygen species’ (ROS) is a generic term that defines a wide variety of oxidant
molecules with vastly different properties and biological functions that range from signalling to …

Two-dimensional electron gases induced by spontaneous and piezoelectric polarization charges in N-and Ga-face AlGaN/GaN heterostructures

…, JR Shealy, NG Weimann, K Chu, M Murphy… - Journal of applied …, 1999 - pubs.aip.org
Carrier concentration profiles of two-dimensional electron gases are investigated in wurtzite,
Ga-face Al x Ga 1−x N/GaN/Al x Ga 1−x N and N-face GaN/Al x Ga 1−x N/GaN …

Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation

…, M DiCuccio, P Kitts, TD Murphy… - Nucleic acids …, 2016 - academic.oup.com
The RefSeq project at the National Center for Biotechnology Information (NCBI) maintains
and curates a publicly available database of annotated genomic, transcript, and protein …

Efficacy and Safety of Trastuzumab as a Single Agent in First-Line Treatment of HER2-Overexpressing Metastatic Breast Cancer

…, M Murphy, WF Novotny, M Burchmore… - Journal of clinical …, 2002 - ascopubs.org
PURPOSE: To evaluate the efficacy and safety of first-line, single-agent trastuzumab in
women with HER2-overexpressing metastatic breast cancer. PATIENTS AND METHODS: One …

[PDF][PDF] Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Aβ and synaptic dysfunction

S Oddo, A Caccamo, JD Shepherd, MP Murphy… - Neuron, 2003 - cell.com
The neuropathological correlates of Alzheimer's disease (AD) include amyloid-β (Aβ) plaques
and neurofibrillary tangles. To study the interaction between Aβ and tau and their effect on …

Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial

J Shepherd, GJ Blauw, MB Murphy, ELEM Bollen… - The lancet, 2002 - thelancet.com
Background Although statins reduce coronary and cerebrovascular morbidity and mortality
in middle-aged individuals, their efficacy and safety in elderly people is not fully established. …

Two dimensional electron gases induced by spontaneous and piezoelectric polarization in undoped and doped AlGaN/GaN heterostructures

…, JR Shealy, NG Weimann, K Chu, M Murphy… - Journal of applied …, 2000 - pubs.aip.org
Two dimensional electron gases in Al x Ga 1−x N/GaN based heterostructures, suitable for
high electron mobility transistors, are induced by strong polarization effects. The sheet carrier …

A reporting system on patients evaluated for coronary artery disease. Report of the Ad Hoc Committee for Grading of Coronary Artery Disease, Council on …

…, VL Gott, LS Griffith, DC McGoon, ML Murphy… - Circulation, 1975 - Am Heart Assoc
I give my enthusiastic support to the" Reporting System on Patients Evaluated for Coronary
Artery Disease" which has been prepared by the committee of the Council on Cardiovascular …