Chronic pain is one of the most prevalent health problems in our modern world, with millions
of people debilitated by conditions such as back pain, headache and arthritis. To address …

Background The senses of touch and proprioception evoke a range of perceptions and rely
on the ability to detect and transduce mechanical force. The molecular and neural …

Sustained pain is a major characteristic of clinical pain disorders, but it is difficult to assess
in isolation from co-occurring cognitive and emotional features in patients. In this study, we …

The brain contains both generalized and stimulus-type-specific representations of aversive
events, but models of how these are integrated and related to subjective experience are …

Yoga, an increasingly popular discipline among Westerners, is frequently used to improve
painful conditions. We investigated possible neuroanatomical underpinnings of the beneficial …

We previously reported that effective treatment of chronic low back pain (CLBP) reversed
abnormal brain structure and functional MRI (fMRI) activity during cognitive task performance, …

Yoga combines postures, breathing, and meditation. Despite reported health benefits, yoga’s
effects on the brain have received little study. We used magnetic resonance imaging to …

Functional Near-Infrared Spectroscopy (fNIRS) is an innovative and promising neuroimaging
modality for studying brain activity in real-world environments. While fNIRS has seen rapid …

Much evidence from pain patients and animal models shows that chronic pain does not exist
in a vacuum but has varied comorbidities and far-reaching consequences. Patients with …

In studies of cognitive processing using tasks with externally directed attention, regions
showing increased (external-task-positive) and decreased or “negative” [default-mode network (…