Site-specific role of catechol-O-methyltransferase in dopamine overflow within prefrontal cortex and dorsal striatum
L Yavich, MM Forsberg, M Karayiorgou… - Journal of …, 2007 - Soc Neuroscience
… inserted in the prefrontal cortex (V, 1.8 mm) via another preliminary drilled opening in the
skull with the following coordinates: AP, 2.47 mm; L, 0.5 mm. We slant the probe (6 from vertical…
skull with the following coordinates: AP, 2.47 mm; L, 0.5 mm. We slant the probe (6 from vertical…
[HTML][HTML] Experimental human placental models for studying uptake, transport and toxicity of micro-and nanoplastics
…, J van Boxel, MBM van Duursen, MM Forsberg… - Science of The Total …, 2023 - Elsevier
Micro- and nanoplastics (MNPs) are ubiquitous in the environment and have recently been
found in human lungs, blood and placenta. However, data on the possible effects of MNPs on …
found in human lungs, blood and placenta. However, data on the possible effects of MNPs on …
Sevoflurane and isoflurane induce structural changes in brain vascular endothelial cells and increase blood− brain barrier permeability: possible link to postoperative …
NK Acharya, EL Goldwaser, MM Forsberg, GA Godsey… - Brain research, 2015 - Elsevier
… Left hemispheres were sliced into 4 mm thick sections for IHC; right hemispheres were
sliced into 2 mm thick sections for scanning electron microscopy. From the left hemispheres a …
sliced into 2 mm thick sections for scanning electron microscopy. From the left hemispheres a …
Design, synthesis and brain uptake of LAT1-targeted amino acid prodrugs of dopamine
…, J Leppänen, M Hämäläinen, MM Forsberg… - Pharmaceutical …, 2013 - Springer
… The mobile phase consisted of acetonitrile (20%, v/v) and 150 mM monobasic sodium
phosphate containing 4.8 mM citric acid monohydrate, 3 mM 1-octanesulfonic acid sodium salt …
phosphate containing 4.8 mM citric acid monohydrate, 3 mM 1-octanesulfonic acid sodium salt …
[HTML][HTML] A smart hospital-driven approach to precision pharmacovigilance
F De Pretis, M van Gils, MM Forsberg - Trends in pharmacological sciences, 2022 - cell.com
Researchers, regulatory agencies, and the pharmaceutical industry are moving towards
precision pharmacovigilance as a comprehensive framework for drug safety assessment, at the …
precision pharmacovigilance as a comprehensive framework for drug safety assessment, at the …
Comparison of seven different anesthesia protocols for nicotine pharmacologic magnetic resonance imaging in rat
… A small craniotomy (∅ 0.5 mm) was performed in the right hemisphere (0.5 mm anterior from
… resonator volume coil (89 mm outer diameter, 72 mm inner diameter) for transmission (both …
… resonator volume coil (89 mm outer diameter, 72 mm inner diameter) for transmission (both …
A cyclopent-2-enecarbonyl group mimics proline at the P2 position of prolyl oligopeptidase inhibitors
…, JA Garcia-Horsman, MM Forsberg… - Journal of medicinal …, 2004 - ACS Publications
… Forsberg. Similar molecular descriptors determine the in vitro drug permeability in
endothelial and epithelial cells. International Journal of Pharmaceutics 2012, 436 (1-2) , 426-443. …
endothelial and epithelial cells. International Journal of Pharmaceutics 2012, 436 (1-2) , 426-443. …
Comparison of in vitro cell models in predicting in vivo brain entry of drugs
…, J Mönkkönen, M Suhonen, MM Forsberg - International journal of …, 2010 - Elsevier
… IC, AgnTho's AB, Lidingö, Sweden) was implanted stereotaxically into the striatum (coordinates
from bregma: AP +0.5 mm; L −3.0 mm; DV −3.8 mm) and fixed to the skull with anchor …
from bregma: AP +0.5 mm; L −3.0 mm; DV −3.8 mm) and fixed to the skull with anchor …
[HTML][HTML] Nigrostriatal 6-hydroxydopamine lesions increase alpha-synuclein levels and permeability in rat colon
…, KM Huttunen, A Kraneveld, MM Forsberg… - Neurobiology of …, 2023 - Elsevier
Increasing evidence suggests that the gut–brain axis plays a crucial role in Parkinson’s disease
(PD). The abnormal accumulation of aggregated alpha-synuclein (aSyn) in the brain is a …
(PD). The abnormal accumulation of aggregated alpha-synuclein (aSyn) in the brain is a …
Binding kinetics and duration of in vivo action of novel prolyl oligopeptidase inhibitors
…, JA Garcia-Horsman, MM Forsberg… - Biochemical …, 2006 - Elsevier
… Slow binding inhibition measurements were made at 23 C in 0.1 M Na-K-phosphate
buffer, pH 7.0, containing 0.1 mM dithiothreitol at an enzyme concentration of 0.14 nM. Z-Gly-Pro-…
buffer, pH 7.0, containing 0.1 mM dithiothreitol at an enzyme concentration of 0.14 nM. Z-Gly-Pro-…