Multiple sclerosis (MS) is classically defined by motor deficits, but it is also associated with
the secondary symptoms of pain, depression, and anxiety. Up to this point modifying these …

Background Chronic neuropathic pain is a common symptom of multiple sclerosis (MS). MOG
35–55 -induced experimental autoimmune encephalomyelitis (EAE) has been used as an …

Maternal infection during pregnancy increases the risk of offspring developing schizophrenia
later in life. Similarly, animal models of maternal immune activation (MIA) induce …

… M-AM, JP, and JW conducted the literature review. M-AM and JP wrote the first draft of
the review. JW, IW, GB, and SD all contributed to and approved the final manuscript. …

… JW Paylor was supported by a studentship from the NSERC. The authors thank Gustavo …
Benson C, Paylor JW, Tenorio G, Winship I, Baker G, Kerr BJ. Voluntary wheel running delays …

Trigeminal neuropathic pain is a well-recognized complication of the demyelinating disease
multiple sclerosis (MS). However, the mechanisms underlying MS-related trigeminal …

Perineuronal nets (PNNs) are highly organized components of the extracellular matrix that
surround a subset of mature neurons in the CNS. These structures play a critical role in …

Perineuronal nets (PNNs) are specialized extracellular matrix structures that surround
subsets of neurons throughout the central nervous system (CNS). They are made up of …

Schizophrenia (SCZ) is a psychiatric disorder that, despite a high prevalence (1% population
worldwide) and burden of disease (1% global burden of disease), has a poorly understood …

Behavioral phenotyping of transgenic and knockout mice requires rigorous, formal analyses.
Well-characterized paradigms can be chosen from the established behavioral …