Local translation in neuronal processes is key to the alteration of synaptic strength necessary
for long-term potentiation, learning, and memory. Here, we present evidence that regulated …

Comparative analysis can provide important insights into complex biological systems. As
demonstrated in the accompanying paper, translating ribosome affinity purification (TRAP) …

Male sex is a strong risk factor for autism spectrum disorder (ASD). The leading theory for a "female
protective effect" (FPE) envisions males and females have "differing thresholds" …

Previous studies have demonstrated that a small subpopulation of brain tumor cells share
key characteristics with neural stem/progenitor cells in terms of phenotype and behavior. …

We have recently developed a novel method for the affinity purification of the complete suite
of translating mRNA from genetically labeled cell populations. This method permits …

A vertebrate homologue of the Fox-1 protein from C. elegans was recently shown to bind to
the element GCAUG and to act as an inhibitor of alternative splicing patterns in muscle. The …

Recent advances have substantially increased the number of genes that are statistically
associated with complex genetic disorders of the CNS such as autism and schizophrenia. It is …

… We would like to thank members of the Dougherty lab, including Mari Gachechiladze and
Din Selmanovic, for thoughtful conversations and comments on the manuscript. This work was …

… Previously, Dougherty and colleagues highlighted this particular brain region based on a
survey of genes reported as autism candidate risk genes 48 . Using a CSEA, we now extend …

Neurons, astrocytes and oligodendrocytes locally regulate protein translation within distal
processes. Here, we tested whether there is regulated local translation within peripheral …