User profiles for G. Drion

Guillaume Drion

ULg/Brandeis University
Verified email at ulg.ac.be
Cited by 1087

Computational implications of biophysical diversity and multiple timescales in neurons and synapses for circuit performance

J Gjorgjieva, G Drion, E Marder - Current opinion in neurobiology, 2016 - Elsevier
Despite advances in experimental and theoretical neuroscience, we are still trying to identify
key biophysical details that are important for characterizing the operation of brain circuits. …

Control across scales by positive and negative feedback

R Sepulchre, G Drion, A Franci - Annual Review of Control …, 2019 - annualreviews.org
… For the sake of mathematical tractability, we follow the approach described by Drion et al.
(16). We assume an infinitesimal step change around a fixed potential V and approximate the …

Ion channel degeneracy enables robust and tunable neuronal firing rates

G Drion, T O'Leary, E Marder - Proceedings of the National …, 2015 - National Acad Sciences
Firing rate is an important means of encoding information in the nervous system. To reliably
encode a wide range of signals, neurons need to achieve a broad range of firing frequencies …

[HTML][HTML] How modeling can reconcile apparently discrepant experimental results: the case of pacemaking in dopaminergic neurons

G Drion, L Massotte, R Sepulchre… - PLoS Computational …, 2011 - journals.plos.org
… , however, the neuron produces only one action potential per oscillation cycle of , which
results in low-frequency single-spike firing rather than bursting in in vitro-like conditions (Drion et…

Implications of cellular models of dopamine neurons for disease

…, AM Oster, EK Pissadaki, G Drion… - Journal of …, 2016 - journals.physiology.org
This review addresses the present state of single-cell models of the firing pattern of
midbrain dopamine neurons and the insights that can be gained from these models into the …

[HTML][HTML] A balance equation determines a switch in neuronal excitability

A Franci, G Drion, V Seutin… - PLoS computational …, 2013 - journals.plos.org
We use the qualitative insight of a planar neuronal phase portrait to detect an excitability
switch in arbitrary conductance-based models from a simple mathematical condition. The …

[HTML][HTML] Introducing neuromodulation in deep neural networks to learn adaptive behaviours

N Vecoven, D Ernst, A Wehenkel, G Drion - PloS one, 2020 - journals.plos.org
Animals excel at adapting their intentions, attention, and actions to the environment, making
them remarkably efficient at interacting with a rich, unpredictable and ever-changing …

An organizing center in a planar model of neuronal excitability

A Franci, G Drion, R Sepulchre - SIAM Journal on Applied Dynamical Systems, 2012 - SIAM
This paper studies the excitability properties of a generalized FitzHugh--Nagumo model. The
model differs from the classical FitzHugh--Nagumo model in that it accounts for the effect of …

Robust and tunable bursting requires slow positive feedback

A Franci, G Drion, R Sepulchre - Journal of …, 2018 - journals.physiology.org
We highlight that the robustness and tunability of a bursting model critically rely on currents
that provide slow positive feedback to the membrane potential. Such currents have the ability …

M‐type channels selectively control bursting in rat dopaminergic neurons

G Drion, M Bonjean, O Waroux… - European Journal of …, 2010 - Wiley Online Library
M‐type channels selectively control bursting in rat dopaminergic neurons - Drion - 2010 - …
Briefly, male Wistar rats (150–200 g) were anesthetized with chloral hydrate (400 mg/kg, ip) …