Mesencephalic astrocyte-derived neurotrophic factor is neurorestorative in rat model of Parkinson's disease

MH Voutilainen, S Bäck, E Pörsti… - Journal of …, 2009 - Soc Neuroscience
… b–e , Photomicrographs of sections from the midbrain showing TH-immunohistochemical
staining of the SN. b–e , TH-positive cells in the SNpc of an intact rat ( b ) or of a 6-OHDA-…

Evidence for an additive neurorestorative effect of simultaneously administered CDNF and GDNF in hemiparkinsonian rats: implications for different mechanism of …

…, P Stepanova, S Bäck, LY Yu, P Lindholm, E Pörsti… - Eneuro, 2017 - eneuro.org
E, Injection of CDNF decreases GRP78 protein levels in striata of 6-OHDA-lesioned rats
compared with PBS (p = 0.2) or GDNF treatment (p < 0.05). The level of expression is expressed …

[HTML][HTML] Genetic contribution to microglial activation in schizophrenia

M Koskuvi, E Pörsti, T Hewitt, N Räsänen, YC Wu… - Molecular …, 2024 - nature.com
Several lines of evidence indicate the involvement of neuroinflammatory processes in the
pathophysiology of schizophrenia (SCZ). Microglia are brain resident immune cells …

Influence of coating thickness on the life of TiN-coated high speed steel cutting tools

E Posti, I Nieminen - Wear, 1989 - Elsevier
The influence of coating thickness on the life of TiN-coated high speed steel cutting tools
has been studied using planing and turning as machining test methods. In the cutting tests …

Genetic contribution to microglial activation in schizophrenia

J Koistinaho, M Koskuvi, E Pörsti, YC Wu, K Trontti… - 2022 - researchsquare.com
… Elina Pörsti assisted in microglia differentiation, performed ICC stainings, WB, and imaging,
processed RNA sequencing data analysis with IPA and GO term analyses, and run CBA. …

Maturation of neuronal activity in caudalized human brain organoids

…, S Abdurakhmanova, S Kuivanen, E Pörsti… - bioRxiv, 2019 - biorxiv.org
E. Action potential waveform of a neuron from 4-month-old organoid. Large action potential
and … E. Sholl analysis of dendritic tree in neurons of different ages. Results are expressed as …

The angular momentum-mass relation: a fundamental law from dwarf irregulars to massive spirals

L Posti, F Fraternali, EM Di Teodoro… - Astronomy & …, 2018 - aanda.org
In a Λ CDM Universe, the specific stellar angular momentum (j * ) and stellar mass (M * ) of a
galaxy are correlated as a consequence of the scaling existing for dark matter haloes (j h ∝ …

Action-based distribution functions for spheroidal galaxy components

L Posti, J Binney, C Nipoti, L Ciotti - Monthly Notices of the Royal …, 2015 - academic.oup.com
… In any power-law potential, we need only to study orbits of one arbitrarily chosen energy
E because each of these orbits can be rescaled to a similar orbit at any given energy E ′ . …

Lower glomerular filtration rate is associated with higher systemic vascular resistance in patients without prevalent kidney disease

…, O Niemelä, J Mustonen, I Pörsti - The Journal of …, 2014 - Wiley Online Library
… , significant associations were found between lower e GFR and higher systolic (P=.… e GFR
and cardiac output or extracellular volume. In the absence of clinical kidney disease, lower e

Paricalcitol treatment and arterial tone in experimental renal insufficiency

…, O Niemelä, J Rysä, H Ruskoaho, I Pörsti - Nephron Experimental …, 2008 - karger.com
… 3E). The relaxation elicited by nifedipine was slightly but significantly augmented in the
NX+Pari rats when compared with sham, while the response to nifedipine was similar in the NX …