User profiles for E. Karaca

Ender Karaca, MD

- Verified email at bswhealth.org - Cited by 4125

Ezgi Karaca

- Verified email at ibg.edu.tr - Cited by 3742

Elif Karaca Atabay

- Verified email at childrens.harvard.edu - Cited by 1147

[HTML][HTML] Evolution of genetic techniques: past, present, and beyond

AA Durmaz, E Karaca, U Demkow, G Toruner… - BioMed research …, 2015 - hindawi.com
Genetics is the study of heredity, which means the study of genes and factors related to all
aspects of genes. The scientific history of genetics began with the works of Gregor Mendel in …

[HTML][HTML] Centers for Mendelian Genomics: A decade of facilitating gene discovery

…, GP Jarvik, Y Jiang, E Johanson, A Jolly, E Karaca… - Genetics in …, 2022 - Elsevier
Purpose Mendelian disease genomic research has undergone a massive transformation
over the past decade. With increasing availability of exome and genome sequencing, the role …

[HTML][HTML] Epigenetic regulation of neurogenesis in the adult hippocampus

M Covic, E Karaca, DC Lie - Heredity, 2010 - nature.com
The dentate gyrus of the hippocampus is an exception to a ‘neurogenesis-unfriendly’environment
of the adult brain. New functional neurons generated in this region contribute to …

[HTML][HTML] The HADDOCK2. 2 web server: user-friendly integrative modeling of biomolecular complexes

…, M Trellet, C Schmitz, PL Kastritis, E Karaca… - Journal of molecular …, 2016 - Elsevier
The prediction of the quaternary structure of biomolecular macromolecules is of paramount
importance for fundamental understanding of cellular processes and drug design. In the era …

[PDF][PDF] A drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases

…, M Jaiswal, WL Charng, T Gambin, E Karaca… - Cell, 2014 - cell.com
Invertebrate model systems are powerful tools for studying human disease owing to their
genetic tractability and ease of screening. We conducted a mosaic genetic screen of lethal …

RBPJκ-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus

…, E Karaca, B Kempkes, E Kremmer… - Journal of …, 2010 - Soc Neuroscience
… c, e, Quantification of the density of PCNA positive cells (c) (**p < 0.01) and the fraction of
PCNA positive cells (e) among the recombined cells (***p < 0.001). d, The overall number of …

[HTML][HTML] Genes that affect brain structure and function identified by rare variant analyses of Mendelian neurologic disease

E Karaca, T Harel, D Pehlivan, SN Jhangiani… - Neuron, 2015 - cell.com
Development of the human nervous system involves complex interactions among fundamental
cellular processes and requires a multitude of genes, many of which remain to be …

Progress on understanding debonding problems in reinforced concrete and steel members strengthened using FRP composites

O Buyukozturk, O Gunes, E Karaca - Construction and Building Materials, 2004 - Elsevier
… Buyukozturk O, Gunes O, Karaca E. Debonding problems in seismic retrofitting of RC beams
using FRP composites. In: Proceedings of the 7th US National Conference on Earthquake …

Primary immunodeficiency diseases: genomic approaches delineate heterogeneous Mendelian disorders

…, E Holmberg, C West, M Burstedt, E Karaca… - Journal of Allergy and …, 2017 - Elsevier
Background Primary immunodeficiency diseases (PIDDs) are clinically and genetically
heterogeneous disorders thus far associated with mutations in more than 300 genes. The clinical …

Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing

…, MJ Silva, M Bienko, N Dojer, Q Wang, E Karaca… - Nature …, 2013 - nature.com
We present a genome-wide approach to map DNA double-strand breaks (DSBs) at nucleotide
resolution by a method we termed BLESS (direct in situ breaks labeling, enrichment on …