User profiles for E. D. Herzog
Erik HerzogProfessor of Biology, Washington University Verified email at wustl.edu Cited by 14129 |
Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neurons
The mammalian suprachiasmatic nucleus (SCN) is a master circadian pacemaker. It is not
known which SCN neurons are autonomous pacemakers or how they synchronize their daily …
known which SCN neurons are autonomous pacemakers or how they synchronize their daily …
A circadian clock in macrophages controls inflammatory immune responses
Time of day-dependent variations of immune system parameters are ubiquitous phenomena
in immunology. The circadian clock has been attributed with coordinating these variations …
in immunology. The circadian clock has been attributed with coordinating these variations …
Circadian rhythms in isolated brain regions
M Abe, ED Herzog, S Yamazaki… - Journal of …, 2002 - Soc Neuroscience
The suprachiasmatic nucleus (SCN) of the mammalian hypothalamus has been referred to
as the master circadian pacemaker that drives daily rhythms in behavior and physiology. …
as the master circadian pacemaker that drives daily rhythms in behavior and physiology. …
[PDF][PDF] Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH
…, N Rensing, P Cliften, DF Wozniak, ED Herzog… - Cell metabolism, 2013 - cell.com
The mammalian Sir2 ortholog Sirt1 plays an important role in metabolic regulation. However,
the role of Sirt1 in the regulation of aging and longevity is still controversial. Here we …
the role of Sirt1 in the regulation of aging and longevity is still controversial. Here we …
Clock controls circadian period in isolated suprachiasmatic nucleus neurons
ED Herzog, JS Takahashi, GD Block - Nature neuroscience, 1998 - nature.com
The suprachiasmatic nucleus (SCN) is the master circadian pacemaker in mammals, and one
molecular regulator of circadian rhythms is the Clock gene. Here we studied the discharge …
molecular regulator of circadian rhythms is the Clock gene. Here we studied the discharge …
[HTML][HTML] Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration
Brain aging is associated with diminished circadian clock output and decreased expression
of the core clock proteins, which regulate many aspects of cellular biochemistry and …
of the core clock proteins, which regulate many aspects of cellular biochemistry and …
Neurons and networks in daily rhythms
ED Herzog - Nature Reviews Neuroscience, 2007 - nature.com
Biological pacemakers dictate our daily schedules in physiology and behaviour. The molecules,
cells and networks that underlie these circadian rhythms can now be monitored using …
cells and networks that underlie these circadian rhythms can now be monitored using …
[PDF][PDF] Come together, right… now: synchronization of rhythms in a mammalian circadian clock
In mammals, the suprachiasmatic nuclei (SCN) of the hypothalamus act as a dominant
circadian pacemaker, coordinating rhythms throughout the body and regulating daily and …
circadian pacemaker, coordinating rhythms throughout the body and regulating daily and …
Temporal precision in the mammalian circadian system: a reliable clock from less reliable neurons
The mammalian SCN contains a biological clock that drives remarkably precise circadian
rhythms in vivo and in vitro. This study asks whether the cycle-to-cycle variability of behavioral …
rhythms in vivo and in vitro. This study asks whether the cycle-to-cycle variability of behavioral …
Circadian rhythm generation and entrainment in astrocytes
LM Prolo, JS Takahashi, ED Herzog - Journal of Neuroscience, 2005 - Soc Neuroscience
In mammals, the master circadian pacemaker is considered the suprachiasmatic nucleus (SCN)
of the hypothalamus. The SCN consists of a heterogeneous population of neurons and …
of the hypothalamus. The SCN consists of a heterogeneous population of neurons and …