User profiles for C. R. Bramham
Clive BramhamDepartment of Biomedicine and Mohn Research Center for the Brain Verified email at uib.no Cited by 14740 |
BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis
CR Bramham, E Messaoudi - Progress in neurobiology, 2005 - Elsevier
Interest in BDNF as an activity-dependent modulator of neuronal structure and function in
the adult brain has intensified in recent years. Localization of BDNF-TrkB to glutamate …
the adult brain has intensified in recent years. Localization of BDNF-TrkB to glutamate …
Brain-derived neurotrophic factor induces long-term potentiation in intact adult hippocampus: requirement for ERK activation coupled to CREB and upregulation of Arc …
…, SP Hunt, TVP Bliss, CR Bramham - Journal of …, 2002 - Soc Neuroscience
Brain-derived neurotrophic factor (BDNF) is implicated in long-term synaptic plasticity in the
adult hippocampus, but the cellular mechanisms are little understood. Here we used …
adult hippocampus, but the cellular mechanisms are little understood. Here we used …
From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning
WJ Tyler, M Alonso, CR Bramham… - Learning & …, 2002 - learnmem.cshlp.org
One of the most rigorously investigated problems in modern neuroscience is to decipher the
mechanisms by which experience-induced changes in the central nervous system are …
mechanisms by which experience-induced changes in the central nervous system are …
Dendritic mRNA: transport, translation and function
CR Bramham, DG Wells - Nature Reviews Neuroscience, 2007 - nature.com
Many cellular functions require the synthesis of a specific protein or functional cohort of
proteins at a specific time and place in the cell. Local protein synthesis in neuronal dendrites is …
proteins at a specific time and place in the cell. Local protein synthesis in neuronal dendrites is …
The immediate early gene arc/arg3. 1: regulation, mechanisms, and function
… Bramham and colleagues have shown that sustained translation of newly induced Arc
mRNA is necessary for cofilin phosphorylation and stable expansion of the F-actin cytoskeleton …
mRNA is necessary for cofilin phosphorylation and stable expansion of the F-actin cytoskeleton …
Sustained Arc/Arg3. 1 synthesis controls long-term potentiation consolidation through regulation of local actin polymerization in the dentate gyrus in vivo
…, G Dagyte, B da Silva, CR Bramham - Journal of …, 2007 - Soc Neuroscience
… Tiron and CR Bramham, unpublished observations) places emphasis on PAK, which
both activates LIMK1 and inhibits activity of the cofilin phosphatase slingshot (Sarmiere and …
both activates LIMK1 and inhibits activity of the cofilin phosphatase slingshot (Sarmiere and …
[HTML][HTML] The Arc of synaptic memory
The immediate early gene Arc is emerging as a versatile, finely tuned system capable of
coupling changes in neuronal activity patterns to synaptic plasticity, thereby optimizing …
coupling changes in neuronal activity patterns to synaptic plasticity, thereby optimizing …
[PDF][PDF] Antidepressant drugs act by directly binding to TRKB neurotrophin receptors
It is unclear how binding of antidepressant drugs to their targets gives rise to the clinical
antidepressant effect. We discovered that the transmembrane domain of tyrosine kinase receptor …
antidepressant effect. We discovered that the transmembrane domain of tyrosine kinase receptor …
BDNF and hippocampal synaptic plasticity
G Leal, CR Bramham, CB Duarte - Vitamins and hormones, 2017 - Elsevier
Brain-derived neurotrophic factor (BDNF) belongs to a family of small secreted proteins that
also include nerve growth factor, neurotrophin 3, and neurotrophin 4. BDNF stands out …
also include nerve growth factor, neurotrophin 3, and neurotrophin 4. BDNF stands out …
Brain-derived neurotrophic factor triggers transcription-dependent, late phase long-term potentiation in vivo
…, T Kanhema, SD Croll, CR Bramham - Journal of …, 2002 - Soc Neuroscience
Acute intrahippocampal infusion of brain-derived neurotrophic factor (BDNF) leads to long-term
potentiation (BDNF-LTP) of synaptic transmission at medial perforant path→granule cell …
potentiation (BDNF-LTP) of synaptic transmission at medial perforant path→granule cell …