Reasons for opioid use among patients with dependence on prescription opioids: the role of chronic pain

J Subst Abuse Treat. 2014 Aug;47(2):140-5. doi: 10.1016/j.jsat.2014.03.004. Epub 2014 Apr 4.

Abstract

The number of individuals seeking treatment for prescription opioid dependence has increased dramatically, fostering a need for research on this population. The aim of this study was to examine reasons for prescription opioid use among 653 participants with and without chronic pain, enrolled in the Prescription Opioid Addiction Treatment Study, a randomized controlled trial of treatment for prescription opioid dependence. Participants identified initial and current reasons for opioid use. Participants with chronic pain were more likely to report pain as their primary initial reason for use; avoiding withdrawal was rated as the most important reason for current use in both groups. Participants with chronic pain rated using opioids to cope with physical pain as more important, and using opioids in response to social interactions and craving as less important, than those without chronic pain. Results highlight the importance of physical pain as a reason for opioid use among patients with chronic pain.

Keywords: Chronic pain; Opioid analgesics; Opioid dependence; Prescription drug abuse; Relapse.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Analgesics, Opioid / administration & dosage*
  • Analgesics, Opioid / adverse effects
  • Analgesics, Opioid / therapeutic use
  • Chronic Pain / drug therapy*
  • Craving
  • Female
  • Humans
  • Male
  • Middle Aged
  • Opioid-Related Disorders / rehabilitation*
  • Prescription Drug Misuse*
  • Substance Withdrawal Syndrome / epidemiology
  • Young Adult

Substances

  • Analgesics, Opioid