The young and the restless: regulation of adult neurogenesis by Wnt signaling

Melody V Wu; René Hen

doi:10.1016/j.stem.2013.01.013

The young and the restless: regulation of adult neurogenesis by Wnt signaling

Cell Stem Cell. 2013 Feb 7;12(2):139-40. doi: 10.1016/j.stem.2013.01.013.

Authors

Melody V Wu¹, René Hen

Affiliation

¹ Department of Psychiatry, Columbia University, New York, NY 10032, USA.

Abstract

Wnt signaling plays a critical role in developmental and adult neurogenesis. In this issue of Cell Stem Cell, Jang et al. (2013) and Seib et al. (2013) show how age and neuronal activity regulate adult hippocampal neurogenesis by inhibiting or activating, respectively, distinct components of the Wnt signaling machinery.

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