Dendrite formation of cerebellar Purkinje cells

Neurochem Res. 2009 Dec;34(12):2078-88. doi: 10.1007/s11064-009-0073-y. Epub 2009 Oct 10.

Abstract

During postnatal cerebellar development, Purkinje cells form the most elaborate dendritic trees among neurons in the brain, which have been of great interest to many investigators. This article overviews various examples of cellular and molecular mechanisms of formation of Purkinje cell dendrites as well as the methodological aspects of investigating those mechanisms.

Publication types

  • Review

MeSH terms

  • Animals
  • Calcium-Calmodulin-Dependent Protein Kinase Type 2 / physiology
  • Carrier Proteins / physiology
  • Cells, Cultured
  • Cerebellum / cytology
  • Cerebellum / growth & development*
  • Dendrites / physiology*
  • Genetic Vectors
  • Homer Scaffolding Proteins
  • Humans
  • Nerve Tissue Proteins
  • Promoter Regions, Genetic / physiology
  • Purkinje Cells / physiology*

Substances

  • Carrier Proteins
  • Homer Scaffolding Proteins
  • Nerve Tissue Proteins
  • Purkinje cell protein L7
  • Calcium-Calmodulin-Dependent Protein Kinase Type 2