Abstract
Huntington's disease can particularly affect people's recognition of disgust from facial expressions1,2, and functional neuroimaging research has demonstrated that facial expressions of disgust consistently engage different brain areas (insula and putamen) than other facial expressions3,4,5. However, it is not known whether these particular brain areas process only facial signals of disgust or disgust signals from multiple modalities. Here we describe evidence, from a patient with insula and putamen damage, for a neural system for recognizing social signals of disgust from multiple modalities.
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References
Sprengelmeyer, R. et al. Brain 119, 1647–1665 (1996).
Gray, J. M., Young, A. W., Barker, W. A., Curtis, A. & Gibson, D. Brain 120, 2029–2038 (1997).
Phillips, M. L. et al. Nature 389, 495–498 (1997).
Phillips, M. L. et al. Proc. R. Soc. Lond. B Biol. Sci. 265, 1809–1817 (1998).
Sprengelmeyer, R., Rausch, M., Eysel, U. T. & Przuntek, H. Proc. R. Soc.Lond. B Biol. Sci. 265, 1927–1931 (1998).
Scott, S. et al. Nature 385, 254–257 (1997).
Calder, A. J. et al. Cognit. Neuropsychol. 13, 699– 745 (1996).
Ekman, P. & Friesen, W. V. Pictures of Facial Affect (Consulting Psychologists, Palo Alto, California, 1976).
Matsumoto, D. & Ekman, P. Japanese and Caucasian Facial Expressions Of Emotion (JACFEE) and Neutral Faces (JACNeuF) (San Francisco State Univ., San Francisco, 1988).
Lang, P. J., Bradley, M. M. & Cuthbert, B. N. International Affective Picture System (IAPS) (NIMH Center for the Study of Emotion and Attention, 1995 ).
Adolphs, R., Tranel, D., Damasio, H. & Damasio, A. Nature 372, 669–672 (1994).
Chikama, M., McFarland, N. R., Amaral, D. G. & Haber, S. N. J. Neurosci. 15, 9686–9705 (1997).
Small, D. M. et al. Neuroreport 10, 7– 14 (1999).
Rozin, P., Haidt, J. & McCauley, C. R. in Handbook of Emotions (eds. Lewis, M. & Haviland, J.) 575–594 (Guilford, New York, 1993).
Mesulam, M. M. & Mufson, E. J. J. Comp. Neurol. 212, 38–52 ( 1982).
Acknowledgements
We thank NK and his family for their time and assistance. Thanks also to Brian Cox for preparing the graphics.
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Calder, A., Keane, J., Manes, F. et al. Impaired recognition and experience of disgust following brain injury . Nat Neurosci 3, 1077–1078 (2000). https://doi.org/10.1038/80586
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DOI: https://doi.org/10.1038/80586
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