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A common progenitor for neurons and glia persists in rat retina late in development

Abstract

Retrovirus-mediated gene transfer was used to mark cell lineages in vivo in the postnatal rat retina. Labelled clones contained up to three different cell types: three types of neurons or two types of neurons and a Müller glial cell. This indicates that a single retinal progenitor can generate remarkably diverse cell types near the end of development.

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Turner, D., Cepko, C. A common progenitor for neurons and glia persists in rat retina late in development. Nature 328, 131–136 (1987). https://doi.org/10.1038/328131a0

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